chr15 : 60,845,776 – 60,846,719

943 bp 52 TFs 1 linked gene

This 943 bp open chromatin element is linked to RORA and is bound by 52 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
RORA		383.1 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

52 transcription factors

Ahr::Arnt 1 dataset

Motif DE_72h DE_72h-AhrArnt_MA0006.2 5 bp overlap

BHLHE22 1 dataset

Motif DE_72h DE_72h-BHLHE22_MA1635.2 6 bp overlap

Bhlha15 1 dataset

Motif DE_72h DE_72h-Bhlha15_MA1472.3 8 bp overlap

CDX1 1 dataset

Motif DE_72h DE_72h-CDX1_MA0878.3 10 bp overlap

CDX2 1 dataset

Motif DE_72h DE_72h-CDX2_MA0465.3 8 bp overlap

CDX4 1 dataset

Motif DE_72h DE_72h-CDX4_MA1473.2 9 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 227 bp overlap

EZH2 1 dataset

ChIP A-1847 GSE95643.EZH2.A-1847 353 bp overlap

FOSL2 1 dataset

Motif DE_72h DE_72h-FOSL2_MA0478.2 10 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 715 bp overlap

ChIP DE DE-FOXA2-2 494 bp overlap

GATA1::TAL1 3 datasets

Motif DE_48h DE_48h-GATA1TAL1_MA0140.3 17 bp overlap

Motif DE_60h DE_60h-GATA1TAL1_MA0140.3 17 bp overlap

Motif DE_72h DE_72h-GATA1TAL1_MA0140.3 17 bp overlap

GATA4 8 datasets

ChIP DE DE-GATA4-1 886 bp overlap

ChIP DE DE-GATA4-2 887 bp overlap

Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap

Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap

Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap

ChIP foregut GSE117136.GATA4.foregut 739 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 777 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 249 bp overlap

GATA6 9 datasets

ChIP AGS GSE51705.GATA6.AGS 200 bp overlap

ChIP DE DE-GATA6-1 770 bp overlap

ChIP DE DE-GATA6-2 872 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 880 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 792 bp overlap

ChIP foregut GSE117136.GATA6.foregut 762 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 508 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 640 bp overlap

ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 306 bp overlap

GCM1 1 dataset

Motif DE_72h DE_72h-GCM1_MA0646.2 10 bp overlap

HNF1B 1 dataset

ChIP foregut GSE117136.HNF1B.foregut 388 bp overlap

HOXA10 1 dataset

Motif DE_72h DE_72h-HOXA10_MA0899.2 9 bp overlap

HOXB13 1 dataset

Motif DE_72h DE_72h-HOXB13_MA0901.3 9 bp overlap

HOXC10 1 dataset

Motif DE_72h DE_72h-HOXC10_MA0905.2 9 bp overlap

HOXC12 1 dataset

Motif DE_72h DE_72h-HOXC12_MA0906.2 10 bp overlap

HOXD10 1 dataset

Motif DE_72h DE_72h-HOXD10_MA1506.2 10 bp overlap

HOXD9 1 dataset

Motif DE_72h DE_72h-HOXD9_MA0913.3 9 bp overlap

Hmga1 1 dataset

Motif DE_72h DE_72h-Hmga1_MA2124.1 8 bp overlap

KLF12 1 dataset

Motif DE_72h DE_72h-KLF12_MA0742.2 9 bp overlap

KLF3 1 dataset

Motif DE_72h DE_72h-KLF3_MA1516.2 10 bp overlap

MEF2A 1 dataset

Motif DE_72h DE_72h-MEF2A_MA0052.5 10 bp overlap

MEF2B 1 dataset

Motif DE_72h DE_72h-MEF2B_MA0660.1 12 bp overlap

MEF2C 1 dataset

Motif DE_72h DE_72h-MEF2C_MA0497.2 11 bp overlap

MEF2D 1 dataset

Motif DE_72h DE_72h-MEF2D_MA0773.1 12 bp overlap

MYF5 1 dataset

Motif DE_72h DE_72h-MYF5_MA1641.2 8 bp overlap

NEUROD1 1 dataset

Motif DE_72h DE_72h-NEUROD1_MA1109.2 8 bp overlap

Neurod2 2 datasets

Motif DE_72h DE_72h-Neurod2_MA0668.3 8 bp overlap

Motif DE_72h DE_72h-Neurod2_MA1993.2 6 bp overlap

Olig2 1 dataset

Motif DE_72h DE_72h-Olig2_MA1997.2 6 bp overlap

PHOX2B 1 dataset

Motif DE_72h DE_72h-PHOX2B_MA0681.3 12 bp overlap

Ptf1A 1 dataset

Motif DE_72h DE_72h-Ptf1A_MA1619.2 8 bp overlap

RUNX3 3 datasets

Motif DE_48h DE_48h-RUNX3_MA0684.3 8 bp overlap

Motif DE_60h DE_60h-RUNX3_MA0684.3 8 bp overlap

Motif DE_72h DE_72h-RUNX3_MA0684.3 8 bp overlap

Rarg 3 datasets

Motif DE_48h DE_48h-Rarg_MA0860.1 17 bp overlap

Motif DE_60h DE_60h-Rarg_MA0860.1 17 bp overlap

Motif DE_72h DE_72h-Rarg_MA0860.1 17 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 219 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 943 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 748 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 780 bp overlap

SMAD3 1 dataset

ChIP endoderm GSE29422.SMAD3.endoderm 197 bp overlap

SMAD4 1 dataset

ChIP endoderm GSE29422.SMAD4.endoderm 289 bp overlap

SOX15 1 dataset

Motif DE_72h DE_72h-SOX15_MA1152.2 7 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 339 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 525 bp overlap

STAT1::STAT2 1 dataset

Motif DE_72h DE_72h-STAT1STAT2_MA0517.2 13 bp overlap

Sox6 2 datasets

Motif DE_72h DE_72h-Sox6_MA0515.1 10 bp overlap

Tbx6 1 dataset

Motif DE_72h DE_72h-Tbx6_MA1567.3 9 bp overlap

Tcf12 1 dataset

Motif DE_72h DE_72h-Tcf12_MA0521.3 6 bp overlap

Twist2 1 dataset

Motif DE_72h DE_72h-Twist2_MA0633.3 6 bp overlap

ZBTB18 1 dataset

Motif DE_72h DE_72h-ZBTB18_MA0698.2 11 bp overlap

ZNF768 3 datasets

Motif DE_48h DE_48h-ZNF768_MA1731.2 9 bp overlap

Motif DE_60h DE_60h-ZNF768_MA1731.2 9 bp overlap

Motif DE_72h DE_72h-ZNF768_MA1731.2 9 bp overlap

Zic2 1 dataset

Motif DE_72h DE_72h-Zic2_MA1629.2 9 bp overlap