chr11 : 44,078,830 – 44,079,335

505 bp 60 TFs 3 linked genes

This 505 bp open chromatin element is linked to EXT2, ALKBH3, and ENSG00000246250 and is bound by 60 transcription factors.

Linked Genes

3 genes

Gene	Dist. to TSS	Distance	Link type
EXT2	16.6 kb	Distal	Multiome
ALKBH3	198.2 kb	Distal	Multiome
ENSG00000246250	198.3 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

60 transcription factors

ARGFX 1 dataset

Motif DE_60h DE_60h-ARGFX_MA1463.2 8 bp overlap

Alx4 1 dataset

Motif DE_60h DE_60h-Alx4_MA0853.2 12 bp overlap

Ar 1 dataset

Motif DE_60h DE_60h-Ar_MA0007.4 16 bp overlap

Arx 1 dataset

Motif DE_60h DE_60h-Arx_MA0874.2 10 bp overlap

BARX1 1 dataset

Motif DE_60h DE_60h-BARX1_MA0875.2 6 bp overlap

BCOR 1 dataset

ChIP WA01 GSE104690.BCOR.WA01 157 bp overlap

BSX 1 dataset

Motif DE_60h DE_60h-BSX_MA0876.2 6 bp overlap

CUX1 1 dataset

Motif DE_60h DE_60h-CUX1_MA0754.3 9 bp overlap

DLX1 1 dataset

Motif DE_60h DE_60h-DLX1_MA0879.3 6 bp overlap

DLX6 1 dataset

Motif DE_60h DE_60h-DLX6_MA0882.2 6 bp overlap

Dlx2 1 dataset

Motif DE_60h DE_60h-Dlx2_MA0885.3 8 bp overlap

Dlx3 1 dataset

Motif DE_60h DE_60h-Dlx3_MA0880.2 6 bp overlap

Dlx4 1 dataset

Motif DE_60h DE_60h-Dlx4_MA0881.2 6 bp overlap

Dlx5 1 dataset

Motif DE_60h DE_60h-Dlx5_MA1476.3 8 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 333 bp overlap

EZH2 2 datasets

ChIP LNCaP GSE39459.EZH2.LNCaP 197 bp overlap

ChIP LNCaP-abl GSE39459.EZH2.LNCaP-abl 92 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 410 bp overlap

ChIP DE DE-FOXA2-2 433 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 501 bp overlap

ChIP DE DE-GATA4-2 505 bp overlap

GATA6 4 datasets

ChIP DE DE-GATA6-1 505 bp overlap

ChIP DE DE-GATA6-2 505 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 496 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 434 bp overlap

GBX2 1 dataset

Motif DE_60h DE_60h-GBX2_MA0890.2 6 bp overlap

HDAC2 1 dataset

ChIP WA01 ENCSR000AVB.HDAC2.WA01 124 bp overlap

HESX1 1 dataset

Motif DE_60h DE_60h-HESX1_MA0894.2 6 bp overlap

HOXA7 1 dataset

Motif DE_60h DE_60h-HOXA7_MA1498.3 6 bp overlap

LBX2 1 dataset

Motif DE_60h DE_60h-LBX2_MA0699.2 6 bp overlap

LHX2 1 dataset

Motif DE_60h DE_60h-LHX2_MA0700.3 6 bp overlap

MED26 1 dataset

ChIP HEK293T GSE121024.MED26.HEK293T 180 bp overlap

MSX1 1 dataset

Motif DE_60h DE_60h-MSX1_MA0666.3 6 bp overlap

MSX2 1 dataset

Motif DE_60h DE_60h-MSX2_MA0708.3 6 bp overlap

Msx3 1 dataset

Motif DE_60h DE_60h-Msx3_MA0709.2 6 bp overlap

NANOG 3 datasets

ChIP H1 ENCFF747ZPQ 241 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 227 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 186 bp overlap

NFIB 1 dataset

Motif DE_60h DE_60h-NFIB_MA1643.2 17 bp overlap

NFIC::TLX1 1 dataset

Motif DE_60h DE_60h-NFICTLX1_MA0119.1 14 bp overlap

NR3C1 1 dataset

Motif DE_60h DE_60h-NR3C1_MA0113.4 15 bp overlap

NR3C2 1 dataset

Motif DE_60h DE_60h-NR3C2_MA0727.2 15 bp overlap

Nobox 1 dataset

Motif DE_60h DE_60h-Nobox_MA0125.2 6 bp overlap

PAX5 1 dataset

ChIP fetal_testis GSE100639.PAX5.fetal_testis 176 bp overlap

Pax7 1 dataset

Motif DE_60h DE_60h-Pax7_MA0680.3 10 bp overlap

Pgr 1 dataset

Motif DE_60h DE_60h-Pgr_MA2323.1 17 bp overlap

Plagl1 1 dataset

Motif DE_60h DE_60h-Plagl1_MA1615.2 8 bp overlap

RAX 1 dataset

Motif DE_60h DE_60h-RAX_MA0718.2 6 bp overlap

Rhox11 1 dataset

Motif DE_60h DE_60h-Rhox11_MA0629.2 9 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 501 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 341 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 377 bp overlap

SOX15 1 dataset

Motif DE_60h DE_60h-SOX15_MA1152.2 7 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 408 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 505 bp overlap

SOX18 2 datasets

Motif DE_60h DE_60h-SOX18_MA1563.2 8 bp overlap

SOX8 2 datasets

Motif DE_60h DE_60h-SOX8_MA0868.3 7 bp overlap

SOX9 2 datasets

Motif DE_60h DE_60h-SOX9_MA0077.2 8 bp overlap

SRY 1 dataset

Motif DE_60h DE_60h-SRY_MA0084.2 7 bp overlap

Sox1 1 dataset

Motif DE_60h DE_60h-Sox1_MA0870.1 15 bp overlap

Sox17 2 datasets

Motif DE_60h DE_60h-Sox17_MA0078.3 10 bp overlap

Sox5 2 datasets

Motif DE_60h DE_60h-Sox5_MA0087.3 8 bp overlap

Sox7 2 datasets

Motif DE_60h DE_60h-Sox7_MA2095.1 10 bp overlap

T 1 dataset

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 179 bp overlap

VENTX 1 dataset

Motif DE_60h DE_60h-VENTX_MA0724.1 9 bp overlap

ZIM3 1 dataset

ChIP HEK293T GSE78099.ZIM3.HEK293T 76 bp overlap

ZNF213 1 dataset

Motif DE_60h DE_60h-ZNF213_MA2121.1 12 bp overlap

ZNF85 1 dataset

Motif DE_60h DE_60h-ZNF85_MA1720.2 12 bp overlap

ZSCAN21 1 dataset

Motif DE_60h DE_60h-ZSCAN21_MA2336.1 7 bp overlap