Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

35 transcription factors

BRD3 1 dataset

ChIP H-1_DE GSE126661.BRD3.H-1_DE 266 bp overlap

BRD4 2 datasets

ChIP Kelly_sensitive GSE103030.BRD4.Kelly_sensitive 771 bp overlap

ChIP SK-N-BE2-C_Naive-veh GSE107706.BRD4.SK-N-BE2-C_Naive-veh 146 bp overlap

CREB1 3 datasets

Motif DE_48h DE_48h-CREB1_MA0018.5 8 bp overlap

Motif DE_60h DE_60h-CREB1_MA0018.5 8 bp overlap

Motif DE_72h DE_72h-CREB1_MA0018.5 8 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 178 bp overlap

FIGLA 2 datasets

Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap

Motif DE_72h DE_72h-FIGLA_MA0820.2 6 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 366 bp overlap

ChIP DE DE-FOXA2-2 647 bp overlap

GATA4 8 datasets

ChIP DE DE-GATA4-1 676 bp overlap

ChIP DE DE-GATA4-2 755 bp overlap

Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap

Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap

Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap

ChIP foregut GSE117136.GATA4.foregut 446 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 409 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 634 bp overlap

GATA5 3 datasets

Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap

Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap

Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap

GATA6 16 datasets

ChIP DE DE-GATA6-1 684 bp overlap

ChIP DE DE-GATA6-2 750 bp overlap

Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap

Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap

Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 367 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 468 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 610 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 480 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 440 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 569 bp overlap

ChIP foregut GSE117136.GATA6.foregut 519 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 366 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 280 bp overlap

ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 294 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 522 bp overlap

Gata3 3 datasets

Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap

Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap

Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap

JUN 1 dataset

ChIP DE_D2 S02-DE-d2-JUN-exp1 558 bp overlap

JUND 3 datasets

Motif DE_48h DE_48h-JUND_MA0492.2 11 bp overlap

Motif DE_60h DE_60h-JUND_MA0492.2 11 bp overlap

Motif DE_72h DE_72h-JUND_MA0492.2 11 bp overlap

MEIS1 2 datasets

Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap

Motif DE_72h DE_72h-MEIS1_MA0498.3 5 bp overlap

MYCN 1 dataset

ChIP NB-1643 GSE138295.MYCN.NB-1643 217 bp overlap

Mecom 3 datasets

Motif DE_48h DE_48h-Mecom_MA0029.2 11 bp overlap

Motif DE_60h DE_60h-Mecom_MA0029.2 11 bp overlap

Motif DE_72h DE_72h-Mecom_MA0029.2 11 bp overlap

NANOG 1 dataset

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 366 bp overlap

PDX1 3 datasets

ChIP hiPSC GSE125768.PDX1.hiPSC 391 bp overlap

ChIP hiPSC_derived_PPs GSE106949.PDX1.hiPSC_derived_PPs 219 bp overlap

ChIP pancreatic-progenitor GSE117136.PDX1.pancreatic-progenitor 435 bp overlap

PITX3 1 dataset

ChIP SH-SY5Y GSE93275.PITX3.SH-SY5Y 355 bp overlap

Ptf1A 2 datasets

Motif DE_60h DE_60h-Ptf1A_MA1620.2 8 bp overlap

Motif DE_72h DE_72h-Ptf1A_MA1620.2 8 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 610 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 546 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 440 bp overlap

SOX13 2 datasets

Motif DE_60h DE_60h-SOX13_MA1120.2 7 bp overlap

Motif DE_72h DE_72h-SOX13_MA1120.2 7 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 638 bp overlap

SOX2 3 datasets

Motif DE_60h DE_60h-SOX2_MA0143.5 7 bp overlap

Motif DE_72h DE_72h-SOX2_MA0143.5 7 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 178 bp overlap

Sox17 2 datasets

Motif DE_60h DE_60h-Sox17_MA0078.3 10 bp overlap

Motif DE_72h DE_72h-Sox17_MA0078.3 10 bp overlap

Sox3 2 datasets

Motif DE_60h DE_60h-Sox3_MA0514.3 7 bp overlap

Motif DE_72h DE_72h-Sox3_MA0514.3 7 bp overlap

Sox5 2 datasets

Motif DE_60h DE_60h-Sox5_MA0087.3 8 bp overlap

Motif DE_72h DE_72h-Sox5_MA0087.3 8 bp overlap

T 1 dataset

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 235 bp overlap

THRB 2 datasets

Motif DE_60h DE_60h-THRB_MA1576.2 18 bp overlap

Motif DE_72h DE_72h-THRB_MA1576.2 18 bp overlap

TRPS1 3 datasets

Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap

Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap

Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap

ZEB1 2 datasets

Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap

Motif DE_72h DE_72h-ZEB1_MA0103.4 6 bp overlap

ZKSCAN1 1 dataset

Motif DE_72h DE_72h-ZKSCAN1_MA1585.2 9 bp overlap

ZNF324 2 datasets

Motif DE_60h DE_60h-ZNF324_MA1977.2 14 bp overlap

Motif DE_72h DE_72h-ZNF324_MA1977.2 14 bp overlap

ZNF341 2 datasets

Motif DE_60h DE_60h-ZNF341_MA1655.2 8 bp overlap

Motif DE_72h DE_72h-ZNF341_MA1655.2 8 bp overlap

ZNF677 3 datasets

Motif DE_48h DE_48h-ZNF677_MA2101.1 12 bp overlap

Motif DE_60h DE_60h-ZNF677_MA2101.1 12 bp overlap

Motif DE_72h DE_72h-ZNF677_MA2101.1 12 bp overlap

Gene	Expression	Dist. to TSS	Distance	Link type
SEC61B		255.3 kb	Distal	Multiome
ALG2		255.6 kb	Distal	Multiome

Genome Browser