Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

38 transcription factors

Arid3a 3 datasets

Motif DE_48h DE_48h-Arid3a_MA0151.1 6 bp overlap

Motif DE_60h DE_60h-Arid3a_MA0151.1 6 bp overlap

Motif DE_72h DE_72h-Arid3a_MA0151.1 6 bp overlap

BACH2 3 datasets

Motif DE_48h DE_48h-BACH2_MA1470.2 19 bp overlap

Motif DE_60h DE_60h-BACH2_MA1470.2 19 bp overlap

Motif DE_72h DE_72h-BACH2_MA1470.2 19 bp overlap

Crx 3 datasets

Motif DE_48h DE_48h-Crx_MA0467.3 6 bp overlap

Motif DE_60h DE_60h-Crx_MA0467.3 6 bp overlap

Motif DE_72h DE_72h-Crx_MA0467.3 6 bp overlap

Dmbx1 3 datasets

Motif DE_48h DE_48h-Dmbx1_MA0883.2 10 bp overlap

Motif DE_60h DE_60h-Dmbx1_MA0883.2 10 bp overlap

Motif DE_72h DE_72h-Dmbx1_MA0883.2 10 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 351 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 710 bp overlap

ChIP DE DE-FOXA2-2 791 bp overlap

GATA1 1 dataset

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 175 bp overlap

GATA2 1 dataset

ChIP TF1 GSE73207.GATA2.TF1 299 bp overlap

GATA3 1 dataset

ChIP Kelly GSE65664.GATA3.Kelly 161 bp overlap

GATA4 5 datasets

ChIP DE DE-GATA4-1 712 bp overlap

ChIP DE DE-GATA4-2 781 bp overlap

ChIP Hep-G2 GSE135714.GATA4.Hep-G2 272 bp overlap

ChIP foregut GSE117136.GATA4.foregut 540 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 517 bp overlap

GATA6 9 datasets

ChIP DE DE-GATA6-1 683 bp overlap

ChIP DE DE-GATA6-2 864 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 393 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 581 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 397 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 470 bp overlap

ChIP foregut GSE117136.GATA6.foregut 511 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 431 bp overlap

ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 321 bp overlap

GSC 3 datasets

Motif DE_48h DE_48h-GSC_MA0648.2 6 bp overlap

Motif DE_60h DE_60h-GSC_MA0648.2 6 bp overlap

Motif DE_72h DE_72h-GSC_MA0648.2 6 bp overlap

GSC2 3 datasets

Motif DE_48h DE_48h-GSC2_MA0891.2 6 bp overlap

Motif DE_60h DE_60h-GSC2_MA0891.2 6 bp overlap

Motif DE_72h DE_72h-GSC2_MA0891.2 6 bp overlap

JUND 3 datasets

Motif DE_48h DE_48h-JUND_MA0492.2 11 bp overlap

Motif DE_60h DE_60h-JUND_MA0492.2 11 bp overlap

Motif DE_72h DE_72h-JUND_MA0492.2 11 bp overlap

KLF9 3 datasets

Motif DE_48h DE_48h-KLF9_MA1107.3 11 bp overlap

Motif DE_60h DE_60h-KLF9_MA1107.3 11 bp overlap

Motif DE_72h DE_72h-KLF9_MA1107.3 11 bp overlap

MEIS1 3 datasets

Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap

Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap

Motif DE_72h DE_72h-MEIS1_MA0498.3 5 bp overlap

MSANTD3 3 datasets

Motif DE_48h DE_48h-MSANTD3_MA1523.2 7 bp overlap

Motif DE_60h DE_60h-MSANTD3_MA1523.2 7 bp overlap

Motif DE_72h DE_72h-MSANTD3_MA1523.2 7 bp overlap

NEUROD1 1 dataset

ChIP D341-Med_shGFP GSE92582.NEUROD1.D341-Med_shGFP 404 bp overlap

NR1H2::RXRA 1 dataset

Motif DE_60h DE_60h-NR1H2RXRA_MA0115.1 17 bp overlap

OSR2 2 datasets

Motif DE_60h DE_60h-OSR2_MA1646.2 8 bp overlap

Motif DE_72h DE_72h-OSR2_MA1646.2 8 bp overlap

OTX1 3 datasets

Motif DE_48h DE_48h-OTX1_MA0711.2 6 bp overlap

Motif DE_60h DE_60h-OTX1_MA0711.2 6 bp overlap

Motif DE_72h DE_72h-OTX1_MA0711.2 6 bp overlap

OTX2 1 dataset

ChIP retina_Hu7 GSE137311.OTX2.retina_Hu7 537 bp overlap

PBX3 3 datasets

Motif DE_48h DE_48h-PBX3_MA1114.2 11 bp overlap

Motif DE_60h DE_60h-PBX3_MA1114.2 11 bp overlap

Motif DE_72h DE_72h-PBX3_MA1114.2 11 bp overlap

PITX1 3 datasets

Motif DE_48h DE_48h-PITX1_MA0682.3 6 bp overlap

Motif DE_60h DE_60h-PITX1_MA0682.3 6 bp overlap

Motif DE_72h DE_72h-PITX1_MA0682.3 6 bp overlap

PITX2 3 datasets

Motif DE_48h DE_48h-PITX2_MA1547.2 8 bp overlap

Motif DE_60h DE_60h-PITX2_MA1547.2 8 bp overlap

Motif DE_72h DE_72h-PITX2_MA1547.2 8 bp overlap

PITX3 3 datasets

Motif DE_48h DE_48h-PITX3_MA0714.2 6 bp overlap

Motif DE_60h DE_60h-PITX3_MA0714.2 6 bp overlap

Motif DE_72h DE_72h-PITX3_MA0714.2 6 bp overlap

PKNOX1 3 datasets

Motif DE_48h DE_48h-PKNOX1_MA0782.3 10 bp overlap

Motif DE_60h DE_60h-PKNOX1_MA0782.3 10 bp overlap

Motif DE_72h DE_72h-PKNOX1_MA0782.3 10 bp overlap

RHOXF1 3 datasets

Motif DE_48h DE_48h-RHOXF1_MA0719.2 6 bp overlap

Motif DE_60h DE_60h-RHOXF1_MA0719.2 6 bp overlap

Motif DE_72h DE_72h-RHOXF1_MA0719.2 6 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 448 bp overlap

SMAD2_3 1 dataset

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 227 bp overlap

SMAD3 1 dataset

ChIP endoderm GSE29422.SMAD3.endoderm 156 bp overlap

SOX15 3 datasets

Motif DE_48h DE_48h-SOX15_MA1152.2 7 bp overlap

Motif DE_60h DE_60h-SOX15_MA1152.2 7 bp overlap

Motif DE_72h DE_72h-SOX15_MA1152.2 7 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 549 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 400 bp overlap

TAL1 4 datasets

ChIP K-562_dCas9-KRAB GSE132212.TAL1.K-562_dCas9-KRAB 180 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.TAL1.K-562_dCas9-LSD1 291 bp overlap

ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 344 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 366 bp overlap

ZNF449 3 datasets

Motif DE_48h DE_48h-ZNF449_MA1656.2 10 bp overlap

Motif DE_60h DE_60h-ZNF449_MA1656.2 10 bp overlap

Motif DE_72h DE_72h-ZNF449_MA1656.2 10 bp overlap

ZSCAN31 3 datasets

Motif DE_48h DE_48h-ZSCAN31_MA1722.2 18 bp overlap

Motif DE_60h DE_60h-ZSCAN31_MA1722.2 18 bp overlap

Motif DE_72h DE_72h-ZSCAN31_MA1722.2 18 bp overlap

Zfp335 3 datasets

Motif DE_48h DE_48h-Zfp335_MA2002.2 7 bp overlap

Motif DE_60h DE_60h-Zfp335_MA2002.2 7 bp overlap

Motif DE_72h DE_72h-Zfp335_MA2002.2 7 bp overlap

Genome Browser