chr5 : 146,700,463 – 146,701,149

686 bp 52 TFs 1 linked gene

This 686 bp open chromatin element is linked to KRT8P48 and is bound by 52 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
KRT8P48		6.5 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

52 transcription factors

ASCL1 1 dataset

Motif DE_12h DE_12h-ASCL1_MA1631.2 9 bp overlap

CDX4 1 dataset

Motif DE_12h DE_12h-CDX4_MA1473.2 9 bp overlap

DMRTA2 1 dataset

Motif DE_12h DE_12h-DMRTA2_MA1478.2 6 bp overlap

EOMES 2 datasets

ChIP hESC GSE26097.EOMES.hESC 168 bp overlap

ChIP hESC GSE26097.EOMES.hESC 167 bp overlap

EP300 1 dataset

ChIP neural ENCSR843ZUP.EP300.neural 148 bp overlap

FIGLA 1 dataset

Motif DE_12h DE_12h-FIGLA_MA0820.2 6 bp overlap

GATA1::TAL1 1 dataset

Motif DE_12h DE_12h-GATA1TAL1_MA0140.3 17 bp overlap

GATA2 1 dataset

Motif DE_12h DE_12h-GATA2_MA0036.4 7 bp overlap

GATA4 3 datasets

ChIP DE DE-GATA4-1 458 bp overlap

ChIP DE DE-GATA4-2 315 bp overlap

Motif DE_12h DE_12h-GATA4_MA0482.3 8 bp overlap

GATA5 1 dataset

Motif DE_12h DE_12h-GATA5_MA0766.3 8 bp overlap

GATA6 10 datasets

ChIP DE DE-GATA6-1 467 bp overlap

ChIP DE DE-GATA6-2 396 bp overlap

Motif DE_12h DE_12h-GATA6_MA1104.3 8 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 623 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 528 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 541 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 214 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 569 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 658 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 482 bp overlap

Gata3 1 dataset

Motif DE_12h DE_12h-Gata3_MA0037.5 8 bp overlap

HIC2 1 dataset

Motif DE_12h DE_12h-HIC2_MA0738.2 6 bp overlap

HOXA10 1 dataset

Motif DE_12h DE_12h-HOXA10_MA0899.2 9 bp overlap

HOXB9 1 dataset

Motif DE_12h DE_12h-HOXB9_MA1503.2 9 bp overlap

HOXC10 1 dataset

Motif DE_12h DE_12h-HOXC10_MA0905.2 9 bp overlap

HOXC12 1 dataset

Motif DE_12h DE_12h-HOXC12_MA0906.2 10 bp overlap

HOXC13 1 dataset

Motif DE_12h DE_12h-HOXC13_MA0907.2 9 bp overlap

HOXC9 1 dataset

Motif DE_12h DE_12h-HOXC9_MA0485.3 9 bp overlap

HOXD10 1 dataset

Motif DE_12h DE_12h-HOXD10_MA1506.2 10 bp overlap

HOXD11 1 dataset

Motif DE_12h DE_12h-HOXD11_MA0908.2 9 bp overlap

HOXD12 1 dataset

Motif DE_12h DE_12h-HOXD12_MA0873.2 10 bp overlap

Hoxa11 1 dataset

Motif DE_12h DE_12h-Hoxa11_MA0911.2 9 bp overlap

JUN 1 dataset

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 412 bp overlap

JUNB 1 dataset

ChIP Karpas-299 GSE151413.JUNB.Karpas-299 681 bp overlap

KLF3 1 dataset

Motif DE_12h DE_12h-KLF3_MA1516.2 10 bp overlap

NANOG 2 datasets

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 410 bp overlap

ChIP hESC GSE18292.NANOG.hESC 135 bp overlap

POU5F1 1 dataset

ChIP DE_D1 DED1-OCT4_Batch_II 280 bp overlap

Ptf1A 1 dataset

Motif DE_12h DE_12h-Ptf1A_MA1620.2 8 bp overlap

RAD21 1 dataset

ChIP neural ENCSR198ZYJ.RAD21.neural 65 bp overlap

RARB 1 dataset

Motif DE_12h DE_12h-RARB_MA1552.2 13 bp overlap

REST 2 datasets

ChIP neural ENCSR000BTV.REST.neural 109 bp overlap

ChIP neural cell ENCFF882LXX 79 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 499 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 542 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 319 bp overlap

SMAD2_3 1 dataset

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 435 bp overlap

SNAI1 1 dataset

Motif DE_12h DE_12h-SNAI1_MA1558.2 7 bp overlap

SNAI3 1 dataset

Motif DE_12h DE_12h-SNAI3_MA1559.2 9 bp overlap

STAT1 1 dataset

ChIP HeLa-S3 ENCSR000EZK.STAT1.HeLa-S3 156 bp overlap

Stat5b 1 dataset

Motif DE_12h DE_12h-Stat5b_MA1625.2 9 bp overlap

T 1 dataset

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 325 bp overlap

TAF1 2 datasets

ChIP neural cell ENCFF468SPD 574 bp overlap

ChIP neural cell ENCFF468SPD 372 bp overlap

TCF12 1 dataset

Motif DE_12h DE_12h-TCF12_MA1648.2 7 bp overlap

TCF3 1 dataset

Motif DE_12h DE_12h-TCF3_MA0522.4 7 bp overlap

TCF4 1 dataset

Motif DE_12h DE_12h-TCF4_MA0830.3 8 bp overlap

TEAD1 1 dataset

ChIP HEK293_siE1A GSE130135.TEAD1.HEK293_siE1A 148 bp overlap

TEAD4 1 dataset

ChIP HEK293_siE1A GSE130135.TEAD4.HEK293_siE1A 171 bp overlap

TP53 1 dataset

ChIP hESC_DAMAGED GSE39912.TP53.hESC_DAMAGED 216 bp overlap

TRPS1 1 dataset

Motif DE_12h DE_12h-TRPS1_MA1970.2 8 bp overlap

ZEB1 1 dataset

Motif DE_12h DE_12h-ZEB1_MA0103.4 6 bp overlap

ZNF157 1 dataset

Motif DE_12h DE_12h-ZNF157_MA2331.1 21 bp overlap

ZNF214 1 dataset

Motif DE_12h DE_12h-ZNF214_MA1975.2 13 bp overlap

ZNF8 1 dataset

Motif DE_12h DE_12h-ZNF8_MA1718.1 20 bp overlap

ZSCAN31 1 dataset

Motif DE_12h DE_12h-ZSCAN31_MA1722.2 18 bp overlap