chr4 : 94,382,686 – 94,383,584
898 bp 56 TFs 3 linked genes
This 898 bp open chromatin element is linked to PDLIM5, SMARCAD1, and SMARCAD1-DT and is bound by 56 transcription factors.
Linked Genes
3 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
PDLIM5 68.7 kb Distal Multiome
SMARCAD1 175.6 kb Distal Multiome
SMARCAD1-DT 175.6 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr4:94,377,686 – 94,388,584
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
56 transcription factors
Source
Cell type
Atoh1 1 dataset
Motif DE_24h DE_24h-Atoh1_MA1467.3 7 bp overlap
CEBPA 2 datasets
Motif DE_12h DE_12h-CEBPA_MA0102.5 10 bp overlap
Motif DE_24h DE_24h-CEBPA_MA0102.5 10 bp overlap
CEBPD 2 datasets
Motif DE_12h DE_12h-CEBPD_MA0836.3 8 bp overlap
Motif DE_24h DE_24h-CEBPD_MA0836.3 8 bp overlap
CREB1 2 datasets
Motif DE_12h DE_12h-CREB1_MA0018.5 8 bp overlap
Motif DE_24h DE_24h-CREB1_MA0018.5 8 bp overlap
CTCF 11 datasets
Motif DE_12h DE_12h-CTCF_MA1929.2 31 bp overlap
Motif DE_12h DE_12h-CTCF_MA1930.2 33 bp overlap
Motif DE_24h DE_24h-CTCF_MA1929.2 31 bp overlap
Motif DE_24h DE_24h-CTCF_MA1930.2 33 bp overlap
Motif DE_36h DE_36h-CTCF_MA1929.2 31 bp overlap
Motif DE_36h DE_36h-CTCF_MA1930.2 33 bp overlap
Motif DE_48h DE_48h-CTCF_MA1929.2 31 bp overlap
Motif DE_48h DE_48h-CTCF_MA1930.2 33 bp overlap
Motif DE_60h DE_60h-CTCF_MA1929.2 31 bp overlap
Motif DE_60h DE_60h-CTCF_MA1930.2 33 bp overlap
Motif DE_72h DE_72h-CTCF_MA1929.2 31 bp overlap
E2F8 6 datasets
Motif DE_12h DE_12h-E2F8_MA0865.3 9 bp overlap
Motif DE_24h DE_24h-E2F8_MA0865.3 9 bp overlap
Motif DE_36h DE_36h-E2F8_MA0865.3 9 bp overlap
Motif DE_48h DE_48h-E2F8_MA0865.3 9 bp overlap
Motif DE_60h DE_60h-E2F8_MA0865.3 9 bp overlap
Motif DE_72h DE_72h-E2F8_MA0865.3 9 bp overlap
FOXA2 3 datasets
ChIP DE DE-FOXA2-1 845 bp overlap
ChIP DE DE-FOXA2-2 609 bp overlap
ChIP DE DE-FOXA2-2 87 bp overlap
GATA2 1 dataset
Motif DE_12h DE_12h-GATA2_MA0036.4 7 bp overlap
GATA4 2 datasets
ChIP DE DE-GATA4-1 618 bp overlap
ChIP DE DE-GATA4-2 785 bp overlap
GATA6 9 datasets
ChIP DE DE-GATA6-1 694 bp overlap
ChIP DE DE-GATA6-2 632 bp overlap
ChIP DE DE-GATA6-2 82 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 601 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 540 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 614 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 594 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 491 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 627 bp overlap
HAND2 1 dataset
Motif DE_24h DE_24h-HAND2_MA1638.2 6 bp overlap
HIC2 1 dataset
Motif DE_24h DE_24h-HIC2_MA0738.2 6 bp overlap
HOXB13 6 datasets
Motif DE_12h DE_12h-HOXB13_MA0901.3 9 bp overlap
Motif DE_24h DE_24h-HOXB13_MA0901.3 9 bp overlap
Motif DE_36h DE_36h-HOXB13_MA0901.3 9 bp overlap
Motif DE_48h DE_48h-HOXB13_MA0901.3 9 bp overlap
Motif DE_60h DE_60h-HOXB13_MA0901.3 9 bp overlap
Motif DE_72h DE_72h-HOXB13_MA0901.3 9 bp overlap
Hoxa13 6 datasets
Motif DE_12h DE_12h-Hoxa13_MA0650.4 8 bp overlap
Motif DE_24h DE_24h-Hoxa13_MA0650.4 8 bp overlap
Motif DE_36h DE_36h-Hoxa13_MA0650.4 8 bp overlap
Motif DE_48h DE_48h-Hoxa13_MA0650.4 8 bp overlap
Motif DE_60h DE_60h-Hoxa13_MA0650.4 8 bp overlap
Motif DE_72h DE_72h-Hoxa13_MA0650.4 8 bp overlap
JUN 2 datasets
ChIP DE_D1 S40-DE-d1-JUN-exp2 332 bp overlap
ChIP DE_D2 S02-DE-d2-JUN-exp1 419 bp overlap
KLF1 6 datasets
Motif DE_12h DE_12h-KLF1_MA0493.3 8 bp overlap
Motif DE_24h DE_24h-KLF1_MA0493.3 8 bp overlap
Motif DE_36h DE_36h-KLF1_MA0493.3 8 bp overlap
Motif DE_48h DE_48h-KLF1_MA0493.3 8 bp overlap
Motif DE_60h DE_60h-KLF1_MA0493.3 8 bp overlap
Motif DE_72h DE_72h-KLF1_MA0493.3 8 bp overlap
KLF2 6 datasets
Motif DE_12h DE_12h-KLF2_MA1515.2 8 bp overlap
Motif DE_24h DE_24h-KLF2_MA1515.2 8 bp overlap
Motif DE_36h DE_36h-KLF2_MA1515.2 8 bp overlap
Motif DE_48h DE_48h-KLF2_MA1515.2 8 bp overlap
Motif DE_60h DE_60h-KLF2_MA1515.2 8 bp overlap
Motif DE_72h DE_72h-KLF2_MA1515.2 8 bp overlap
KLF4 6 datasets
Motif DE_12h DE_12h-KLF4_MA0039.5 8 bp overlap
Motif DE_24h DE_24h-KLF4_MA0039.5 8 bp overlap
Motif DE_36h DE_36h-KLF4_MA0039.5 8 bp overlap
Motif DE_48h DE_48h-KLF4_MA0039.5 8 bp overlap
Motif DE_60h DE_60h-KLF4_MA0039.5 8 bp overlap
Motif DE_72h DE_72h-KLF4_MA0039.5 8 bp overlap
KLF5 6 datasets
Motif DE_12h DE_12h-KLF5_MA0599.1 10 bp overlap
Motif DE_24h DE_24h-KLF5_MA0599.1 10 bp overlap
Motif DE_36h DE_36h-KLF5_MA0599.1 10 bp overlap
Motif DE_48h DE_48h-KLF5_MA0599.1 10 bp overlap
Motif DE_60h DE_60h-KLF5_MA0599.1 10 bp overlap
Motif DE_72h DE_72h-KLF5_MA0599.1 10 bp overlap
MAFF 2 datasets
Motif DE_12h DE_12h-MAFF_MA0495.4 11 bp overlap
Motif DE_24h DE_24h-MAFF_MA0495.4 11 bp overlap
MAFK 1 dataset
Motif DE_12h DE_12h-MAFK_MA0496.4 10 bp overlap
MEIS1 2 datasets
Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap
Motif DE_24h DE_24h-MEIS1_MA0498.3 5 bp overlap
MZF1 13 datasets
Motif DE_12h DE_12h-MZF1_MA0056.3 8 bp overlap
Motif DE_12h DE_12h-MZF1_MA0056.3 8 bp overlap
Motif DE_24h DE_24h-MZF1_MA0056.3 8 bp overlap
Motif DE_24h DE_24h-MZF1_MA0056.3 8 bp overlap
Motif DE_24h DE_24h-MZF1_MA0056.3 8 bp overlap
Motif DE_36h DE_36h-MZF1_MA0056.3 8 bp overlap
Motif DE_36h DE_36h-MZF1_MA0056.3 8 bp overlap
Motif DE_48h DE_48h-MZF1_MA0056.3 8 bp overlap
Motif DE_48h DE_48h-MZF1_MA0056.3 8 bp overlap
Motif DE_60h DE_60h-MZF1_MA0056.3 8 bp overlap
Motif DE_60h DE_60h-MZF1_MA0056.3 8 bp overlap
Motif DE_72h DE_72h-MZF1_MA0056.3 8 bp overlap
Motif DE_72h DE_72h-MZF1_MA0056.3 8 bp overlap
Mafb 2 datasets
Motif DE_12h DE_12h-Mafb_MA0117.3 11 bp overlap
Motif DE_24h DE_24h-Mafb_MA0117.3 11 bp overlap
NEUROD1 1 dataset
Motif DE_24h DE_24h-NEUROD1_MA1109.2 8 bp overlap
NEUROG2 1 dataset
Motif DE_24h DE_24h-NEUROG2_MA1642.2 7 bp overlap
NRL 2 datasets
Motif DE_12h DE_12h-NRL_MA0842.3 12 bp overlap
Motif DE_24h DE_24h-NRL_MA0842.3 12 bp overlap
Neurod2 1 dataset
Motif DE_24h DE_24h-Neurod2_MA0668.3 8 bp overlap
Nfat5 6 datasets
Motif DE_12h DE_12h-Nfat5_MA0606.3 8 bp overlap
Motif DE_24h DE_24h-Nfat5_MA0606.3 8 bp overlap
Motif DE_36h DE_36h-Nfat5_MA0606.3 8 bp overlap
Motif DE_48h DE_48h-Nfat5_MA0606.3 8 bp overlap
Motif DE_60h DE_60h-Nfat5_MA0606.3 8 bp overlap
Motif DE_72h DE_72h-Nfat5_MA0606.3 8 bp overlap
Nfatc2 6 datasets
Motif DE_12h DE_12h-Nfatc2_MA0152.3 8 bp overlap
Motif DE_24h DE_24h-Nfatc2_MA0152.3 8 bp overlap
Motif DE_36h DE_36h-Nfatc2_MA0152.3 8 bp overlap
Motif DE_48h DE_48h-Nfatc2_MA0152.3 8 bp overlap
Motif DE_60h DE_60h-Nfatc2_MA0152.3 8 bp overlap
Motif DE_72h DE_72h-Nfatc2_MA0152.3 8 bp overlap
Nr1h3::Rxra 1 dataset
Motif DE_24h DE_24h-Nr1h3Rxra_MA0494.2 16 bp overlap
POU5F1 1 dataset
ChIP DE_D1 DED1-OCT4_Batch_II 575 bp overlap
POU5F1_M 1 dataset
ChIP DE_D1 DED1-OCT4-M_Batch_II 489 bp overlap
Plagl1 6 datasets
Motif DE_12h DE_12h-Plagl1_MA1615.2 8 bp overlap
Motif DE_24h DE_24h-Plagl1_MA1615.2 8 bp overlap
Motif DE_36h DE_36h-Plagl1_MA1615.2 8 bp overlap
Motif DE_48h DE_48h-Plagl1_MA1615.2 8 bp overlap
Motif DE_60h DE_60h-Plagl1_MA1615.2 8 bp overlap
Motif DE_72h DE_72h-Plagl1_MA1615.2 8 bp overlap
RELA 3 datasets
Motif DE_12h DE_12h-RELA_MA0107.1 10 bp overlap
Motif DE_24h DE_24h-RELA_MA0107.1 10 bp overlap
Motif DE_36h DE_36h-RELA_MA0107.1 10 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 258 bp overlap
SMAD2_3 4 datasets
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 252 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 453 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 483 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 511 bp overlap
SMAD3 1 dataset
ChIP BG03_DIFF_48H GSE36578.SMAD3.BG03_DIFF_48H 136 bp overlap
SMARCC1 1 dataset
ChIP DE_D1 S15-DE-d1-BAF155-exp1 249 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 537 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 577 bp overlap
T 2 datasets
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 186 bp overlap
ChIP H9_MESODERM GSE60606.T.H9_MESODERM 184 bp overlap
TBP 6 datasets
Motif DE_12h DE_12h-TBP_MA0108.3 7 bp overlap
Motif DE_24h DE_24h-TBP_MA0108.3 7 bp overlap
Motif DE_36h DE_36h-TBP_MA0108.3 7 bp overlap
Motif DE_48h DE_48h-TBP_MA0108.3 7 bp overlap
Motif DE_60h DE_60h-TBP_MA0108.3 7 bp overlap
Motif DE_72h DE_72h-TBP_MA0108.3 7 bp overlap
TBX19 2 datasets
Motif DE_12h DE_12h-TBX19_MA0804.2 17 bp overlap
Motif DE_24h DE_24h-TBX19_MA0804.2 17 bp overlap
TBXT 2 datasets
Motif DE_12h DE_12h-TBXT_MA0009.2 16 bp overlap
Motif DE_24h DE_24h-TBXT_MA0009.2 16 bp overlap
THRA 1 dataset
Motif DE_24h DE_24h-THRA_MA1969.2 18 bp overlap
TWIST1 1 dataset
Motif DE_24h DE_24h-TWIST1_MA1123.3 8 bp overlap
Yy1 6 datasets
Motif DE_12h DE_12h-Yy1_MA0095.4 8 bp overlap
Motif DE_24h DE_24h-Yy1_MA0095.4 8 bp overlap
Motif DE_36h DE_36h-Yy1_MA0095.4 8 bp overlap
Motif DE_48h DE_48h-Yy1_MA0095.4 8 bp overlap
Motif DE_60h DE_60h-Yy1_MA0095.4 8 bp overlap
Motif DE_72h DE_72h-Yy1_MA0095.4 8 bp overlap
ZFP42 6 datasets
Motif DE_12h DE_12h-ZFP42_MA1651.2 13 bp overlap
Motif DE_24h DE_24h-ZFP42_MA1651.2 13 bp overlap
Motif DE_36h DE_36h-ZFP42_MA1651.2 13 bp overlap
Motif DE_48h DE_48h-ZFP42_MA1651.2 13 bp overlap
Motif DE_60h DE_60h-ZFP42_MA1651.2 13 bp overlap
Motif DE_72h DE_72h-ZFP42_MA1651.2 13 bp overlap
ZNF157 6 datasets
Motif DE_12h DE_12h-ZNF157_MA2331.1 21 bp overlap
Motif DE_24h DE_24h-ZNF157_MA2331.1 21 bp overlap
Motif DE_36h DE_36h-ZNF157_MA2331.1 21 bp overlap
Motif DE_48h DE_48h-ZNF157_MA2331.1 21 bp overlap
Motif DE_60h DE_60h-ZNF157_MA2331.1 21 bp overlap
Motif DE_72h DE_72h-ZNF157_MA2331.1 21 bp overlap
ZNF16 1 dataset
Motif DE_12h DE_12h-ZNF16_MA1654.2 21 bp overlap
ZNF416 1 dataset
Motif DE_24h DE_24h-ZNF416_MA1979.2 10 bp overlap
ZNF528 6 datasets
Motif DE_12h DE_12h-ZNF528_MA1597.1 17 bp overlap
Motif DE_24h DE_24h-ZNF528_MA1597.1 17 bp overlap
Motif DE_24h DE_24h-ZNF528_MA1597.1 17 bp overlap
Motif DE_36h DE_36h-ZNF528_MA1597.1 17 bp overlap
Motif DE_48h DE_48h-ZNF528_MA1597.1 17 bp overlap
Motif DE_60h DE_60h-ZNF528_MA1597.1 17 bp overlap
ZNF582 1 dataset
Motif DE_24h DE_24h-ZNF582_MA1983.2 19 bp overlap
ZNF667 6 datasets
Motif DE_12h DE_12h-ZNF667_MA1984.2 11 bp overlap
Motif DE_24h DE_24h-ZNF667_MA1984.2 11 bp overlap
Motif DE_36h DE_36h-ZNF667_MA1984.2 11 bp overlap
Motif DE_48h DE_48h-ZNF667_MA1984.2 11 bp overlap
Motif DE_60h DE_60h-ZNF667_MA1984.2 11 bp overlap
Motif DE_72h DE_72h-ZNF667_MA1984.2 11 bp overlap
ZNF707 10 datasets
Motif DE_12h DE_12h-ZNF707_MA1715.1 15 bp overlap
Motif DE_12h DE_12h-ZNF707_MA1715.1 15 bp overlap
Motif DE_24h DE_24h-ZNF707_MA1715.1 15 bp overlap
Motif DE_24h DE_24h-ZNF707_MA1715.1 15 bp overlap
Motif DE_36h DE_36h-ZNF707_MA1715.1 15 bp overlap
Motif DE_36h DE_36h-ZNF707_MA1715.1 15 bp overlap
Motif DE_48h DE_48h-ZNF707_MA1715.1 15 bp overlap
Motif DE_48h DE_48h-ZNF707_MA1715.1 15 bp overlap
Motif DE_60h DE_60h-ZNF707_MA1715.1 15 bp overlap
Motif DE_60h DE_60h-ZNF707_MA1715.1 15 bp overlap
Huangfu Lab · Publications · Resources · Contact