Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

44 transcription factors

CEBPD 1 dataset

Motif DE_60h DE_60h-CEBPD_MA0836.3 8 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 281 bp overlap

FIGLA 2 datasets

Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap

Motif DE_72h DE_72h-FIGLA_MA0820.2 6 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 435 bp overlap

ChIP DE DE-FOXA2-2 487 bp overlap

FOXC2 1 dataset

Motif DE_60h DE_60h-FOXC2_MA0846.2 11 bp overlap

FOXD2 1 dataset

Motif DE_60h DE_60h-FOXD2_MA0847.4 11 bp overlap

FOXE1 2 datasets

Motif DE_60h DE_60h-FOXE1_MA1487.3 12 bp overlap

Foxq1 1 dataset

Motif DE_60h DE_60h-Foxq1_MA0040.2 10 bp overlap

GATA4 5 datasets

ChIP DE DE-GATA4-1 467 bp overlap

ChIP DE DE-GATA4-2 565 bp overlap

ChIP foregut GSE117136.GATA4.foregut 369 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 407 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 556 bp overlap

GATA6 13 datasets

ChIP DE DE-GATA6-1 492 bp overlap

ChIP DE DE-GATA6-2 558 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 549 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 561 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 565 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 565 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 562 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 565 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 443 bp overlap

ChIP foregut GSE117136.GATA6.foregut 399 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 363 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 259 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 447 bp overlap

Hand1::Tcf3 1 dataset

Motif DE_60h DE_60h-Hand1Tcf3_MA0092.2 9 bp overlap

Hmga1 1 dataset

Motif DE_60h DE_60h-Hmga1_MA2124.1 8 bp overlap

JUN 4 datasets

ChIP DE_D1 S08-DE-d1-JUN-exp1 339 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 387 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 381 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 263 bp overlap

MAF 1 dataset

Motif DE_60h DE_60h-MAF_MA1520.2 13 bp overlap

MAF::NFE2 1 dataset

Motif DE_60h DE_60h-MAFNFE2_MA0501.2 11 bp overlap

MAFF 1 dataset

Motif DE_60h DE_60h-MAFF_MA0495.4 11 bp overlap

NANOG 1 dataset

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 202 bp overlap

Nfe2l2 1 dataset

Motif DE_60h DE_60h-Nfe2l2_MA0150.3 11 bp overlap

POU1F1 1 dataset

Motif DE_60h DE_60h-POU1F1_MA0784.3 14 bp overlap

POU2F3 2 datasets

Motif DE_60h DE_60h-POU2F3_MA0627.3 9 bp overlap

Motif DE_72h DE_72h-POU2F3_MA0627.3 9 bp overlap

POU3F1 2 datasets

Motif DE_60h DE_60h-POU3F1_MA0786.2 10 bp overlap

Motif DE_72h DE_72h-POU3F1_MA0786.2 10 bp overlap

POU3F3 1 dataset

Motif DE_60h DE_60h-POU3F3_MA0788.1 13 bp overlap

POU4F1 2 datasets

Motif DE_60h DE_60h-POU4F1_MA0790.2 12 bp overlap

Motif DE_72h DE_72h-POU4F1_MA0790.2 12 bp overlap

POU4F2 2 datasets

Motif DE_60h DE_60h-POU4F2_MA0683.2 15 bp overlap

Motif DE_72h DE_72h-POU4F2_MA0683.2 15 bp overlap

POU4F3 2 datasets

Motif DE_60h DE_60h-POU4F3_MA0791.2 12 bp overlap

Motif DE_72h DE_72h-POU4F3_MA0791.2 12 bp overlap

POU5F1 2 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 283 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 255 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 243 bp overlap

SMAD2 3 datasets

Motif DE_60h DE_60h-SMAD2_MA1964.2 6 bp overlap

ChIP endoderm GSE29422.SMAD2.endoderm 214 bp overlap

ChIP hESC_YAP-_activinA_15h GSE99202.SMAD2.hESC_YAP-_activinA_15h 555 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 565 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 565 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 565 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 565 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 565 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 529 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 565 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 560 bp overlap

SMAD4 1 dataset

ChIP endoderm GSE29422.SMAD4.endoderm 282 bp overlap

SOX14 1 dataset

Motif DE_60h DE_60h-SOX14_MA1562.2 9 bp overlap

SOX15 1 dataset

Motif DE_60h DE_60h-SOX15_MA1152.2 7 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 265 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 279 bp overlap

SOX18 1 dataset

Motif DE_60h DE_60h-SOX18_MA1563.2 8 bp overlap

SOX8 1 dataset

Motif DE_60h DE_60h-SOX8_MA0868.3 7 bp overlap

SOX9 1 dataset

Motif DE_60h DE_60h-SOX9_MA0077.2 8 bp overlap

SREBF1 2 datasets

Motif DE_60h DE_60h-SREBF1_MA0829.3 10 bp overlap

Motif DE_72h DE_72h-SREBF1_MA0829.3 10 bp overlap

SRY 1 dataset

Motif DE_60h DE_60h-SRY_MA0084.2 7 bp overlap

Sox5 1 dataset

Motif DE_60h DE_60h-Sox5_MA0087.3 8 bp overlap

Sox6 1 dataset

Motif DE_60h DE_60h-Sox6_MA0515.1 10 bp overlap

Sox7 1 dataset

Motif DE_60h DE_60h-Sox7_MA2095.1 10 bp overlap

ZEB1 2 datasets

Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap

Motif DE_72h DE_72h-ZEB1_MA0103.4 6 bp overlap

Gene	Dist. to TSS	Distance	Link type
VCF2	7.9 kb	Proximal	Proximity
APEX2	152.6 kb	Distal	Multiome
TRO	232.1 kb	Distal	Multiome
MAGEH1	299.2 kb	Distal	Multiome+HiCAR

Genome Browser