chr15:74,720,336–74,720,840

chr15 : 74,720,336 – 74,720,840

504 bp 16 TFs 14 linked genes

This 504 bp open chromatin element is linked to 14 target genes and is bound by 16 transcription factors.

Linked Genes

14 genes

Gene	Expression	Dist. to TSS	Distance	Link type
CYP1A1		4.7 kb	Proximal	Proximity
EDC3		24.6 kb	Distal	Multiome
CSK		61.4 kb	Distal	Multiome
CLK3		122.1 kb	Distal	Multiome
ULK3		122.5 kb	Distal	Multiome
SCAMP2		152.7 kb	Distal	Multiome
MPI		169.4 kb	Distal	Multiome
ARID3B		179.4 kb	Distal	Multiome
FAM219B		186.2 kb	Distal	Multiome
COX5A		217.4 kb	Distal	Multiome
RPP25		236.1 kb	Distal	Multiome
UBL7-DT		259.4 kb	Distal	Multiome
UBL7		259.5 kb	Distal	Multiome
SCAMP5		275.0 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

16 transcription factors

ChIP hMSC-TERT_osteoblast GSE89179.CHD1.hMSC-TERT_osteoblast 235 bp overlap

ChIP T-47D_ETOH_45 GSE62428.CHD8.T-47D_ETOH_45 93 bp overlap

ChIP T-47D_NaCl-isotonic-triptolide GSE111923.CTCF.T-47D_NaCl-isotonic-triptolide 210 bp overlap

Cebpa 2 datasets

ChIP BLaER1 ENCFF460KDD 88 bp overlap

ChIP BLaER1 ENCFF460KDD 290 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 279 bp overlap

ESR1 4 datasets

ChIP Ishikawa_DMSO_D538G_clone3 GSE132426.ESR1.Ishikawa_DMSO_D538G_clone3 84 bp overlap

ChIP Ishikawa_E2_D538G_clone2 GSE132426.ESR1.Ishikawa_E2_D538G_clone2 324 bp overlap

ChIP Ishikawa_siETV4-72h GSE129803.ESR1.Ishikawa_siETV4-72h 220 bp overlap

ChIP MCF-7_SHCTR_E2_TNF GSE59530.ESR1.MCF-7_SHCTR_E2_TNF 122 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 457 bp overlap

ChIP DE DE-GATA4-2 438 bp overlap

GATA6 4 datasets

ChIP DE DE-GATA6-1 455 bp overlap

ChIP DE DE-GATA6-2 504 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 358 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 367 bp overlap

SIN3A 1 dataset

ChIP MCF-7 ENCSR468LUO.SIN3A.MCF-7 237 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 504 bp overlap

SMAD2_3 1 dataset

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 309 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 241 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 336 bp overlap

SREBF2 1 dataset

ChIP HeLa-S3 ENCSR611WZO.SREBF2.HeLa-S3 135 bp overlap

ChIP HEK293T_control GSE128106.YY1.HEK293T_control 219 bp overlap

ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 177 bp overlap