chr11:62,460,403–62,461,004

chr11 : 62,460,403 – 62,461,004

601 bp 20 TFs 16 linked genes

This 601 bp open chromatin element is linked to 16 target genes and is bound by 20 transcription factors.

Linked Genes

16 genes

Gene	Expression	Dist. to TSS	Distance	Link type
AHNAK		86.1 kb	Distal	Multiome
EEF1G		113.1 kb	Distal	Multiome
ASRGL1		123.3 kb	Distal	Multiome
TUT1		130.8 kb	Distal	Multiome
MTA2		141.1 kb	Distal	Multiome
EML3		151.8 kb	Distal	Multiome
B3GAT3		161.2 kb	Distal	Multiome
GANAB		185.9 kb	Distal	Multiome
INTS5		192.5 kb	Distal	Multiome
CSKMT		204.5 kb	Distal	Multiome
UQCC3		210.9 kb	Distal	Multiome
UBXN1		218.3 kb	Distal	Multiome
BSCL2		246.7 kb	Distal	Multiome
HNRNPUL2		266.7 kb	Distal	Multiome
TTC9C		267.7 kb	Distal	Multiome
ZBTB3		293.4 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

20 transcription factors

ChIP CHL-1 GSE95585.BRD4.CHL-1 217 bp overlap

CTCF 3 datasets

ChIP GM23338 ENCFF832KWE 219 bp overlap

ChIP endodermal cell ENCFF471YCZ 123 bp overlap

ChIP hESC_NAIVE GSE69646.CTCF.hESC_NAIVE 337 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 252 bp overlap

FOXA2 1 dataset

ChIP DE DE-FOXA2-1 362 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 530 bp overlap

ChIP DE DE-GATA4-2 593 bp overlap

GATA6 12 datasets

ChIP DE DE-GATA6-1 531 bp overlap

ChIP DE DE-GATA6-2 568 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 511 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 577 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 584 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 552 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 558 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 481 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 520 bp overlap

ChIP foregut GSE117136.GATA6.foregut 457 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 439 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 226 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 300 bp overlap

KDM4C 1 dataset

ChIP KYSE-150 GSE53938.KDM4C.KYSE-150 82 bp overlap

MLLT1 1 dataset

ChIP K562 ENCFF074XRJ 261 bp overlap

NKX2-1 1 dataset

ChIP H9_derived-cIN GSE99937.NKX2-1.H9_derived-cIN 56 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 223 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 585 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 577 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 466 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 480 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 527 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 431 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 590 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 597 bp overlap

SMAD4 1 dataset

ChIP endoderm GSE29422.SMAD4.endoderm 183 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 242 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 499 bp overlap

ZBTB33 3 datasets

ChIP K-562 ENCSR876GXA.ZBTB33.K-562 330 bp overlap

ChIP K562 ENCFF427SDV 363 bp overlap

ChIP K562 ENCFF875HLX 203 bp overlap

ZBTB7A 2 datasets

ChIP K-562 GSE103445.ZBTB7A.K-562 99 bp overlap

ChIP K-562 GSE103445.ZBTB7A.K-562 165 bp overlap

ZNF592 3 datasets

ChIP K-562 ENCSR249BHQ.ZNF592.K-562 449 bp overlap

ChIP K562 ENCFF547OSS 474 bp overlap

ChIP K562 ENCFF547OSS 530 bp overlap

ZNF736 1 dataset

ChIP HEK293T GSE78099.ZNF736.HEK293T 99 bp overlap