Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

49 transcription factors

ATF2 1 dataset

Motif DE_36h DE_36h-ATF2_MA1632.2 10 bp overlap

BHLHE40 1 dataset

ChIP GM12878 ENCSR987MTA.BHLHE40.GM12878 221 bp overlap

CREB1 1 dataset

Motif DE_36h DE_36h-CREB1_MA0018.5 8 bp overlap

CTCF 1 dataset

ChIP anterior-temporal-cortex_adult GSE116825.CTCF.anterior-temporal-cortex_adult 171 bp overlap

DMRTA2 1 dataset

Motif DE_36h DE_36h-DMRTA2_MA1478.2 6 bp overlap

DUX4 1 dataset

Motif DE_36h DE_36h-DUX4_MA0468.1 11 bp overlap

EOMES 2 datasets

ChIP hESC GSE26097.EOMES.hESC 120 bp overlap

ChIP hESC GSE26097.EOMES.hESC 341 bp overlap

EP300 1 dataset

ChIP GM12878 ENCFF242HCG 361 bp overlap

ERF::FOXO1 1 dataset

Motif DE_36h DE_36h-ERFFOXO1_MA1936.2 12 bp overlap

FLI1 3 datasets

ChIP A-673_1_KRAB_GFP GSE106914.FLI1.A-673_1_KRAB_GFP 312 bp overlap

ChIP A-673_2_KRAB_eSOX2_1 GSE106914.FLI1.A-673_2_KRAB_eSOX2_1 231 bp overlap

ChIP A-673_D17 GSE129155.FLI1.A-673_D17 481 bp overlap

FOS::JUN 1 dataset

Motif DE_36h DE_36h-FOSJUN_MA1126.2 10 bp overlap

FOXA2 3 datasets

ChIP DE DE-FOXA2-1 267 bp overlap

ChIP DE DE-FOXA2-1 658 bp overlap

ChIP DE DE-FOXA2-2 983 bp overlap

GATA2 1 dataset

ChIP hiPSC_SLC6ebs GSE107639.GATA2.hiPSC_SLC6ebs 182 bp overlap

GATA4 4 datasets

ChIP DE DE-GATA4-1 625 bp overlap

ChIP DE DE-GATA4-2 956 bp overlap

ChIP foregut GSE117136.GATA4.foregut 259 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 603 bp overlap

GATA6 11 datasets

ChIP DE DE-GATA6-1 100 bp overlap

ChIP DE DE-GATA6-1 547 bp overlap

ChIP DE DE-GATA6-2 958 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 501 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 620 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 389 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 394 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 1057 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 354 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 544 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 376 bp overlap

HNF1B 1 dataset

ChIP foregut GSE117136.HNF1B.foregut 216 bp overlap

HNF4A 1 dataset

Motif DE_36h DE_36h-HNF4A_MA0114.5 9 bp overlap

HNF4G 1 dataset

Motif DE_36h DE_36h-HNF4G_MA0484.3 9 bp overlap

Hand1 1 dataset

Motif DE_36h DE_36h-Hand1_MA2123.1 9 bp overlap

Hmx2 1 dataset

Motif DE_36h DE_36h-Hmx2_MA0897.2 15 bp overlap

Hmx3 1 dataset

Motif DE_36h DE_36h-Hmx3_MA0898.2 9 bp overlap

IKZF1 1 dataset

ChIP GM12878 ENCFF753XDO 569 bp overlap

ISL2 1 dataset

Motif DE_36h DE_36h-ISL2_MA0914.2 6 bp overlap

JUN 2 datasets

Motif DE_36h DE_36h-JUN_MA0488.2 10 bp overlap

ChIP DE_D1 S08-DE-d1-JUN-exp1 263 bp overlap

MEIS1 2 datasets

Motif DE_36h DE_36h-MEIS1_MA0498.3 5 bp overlap

MTA2 3 datasets

ChIP GM12878 ENCFF615CWQ 571 bp overlap

ChIP GM12878 ENCFF615CWQ 424 bp overlap

ChIP GM12878 ENCSR293QAR.MTA2.GM12878 373 bp overlap

NOTCH1 1 dataset

ChIP HPBALL GSE39263.NOTCH1.HPBALL 179 bp overlap

NR4A1 1 dataset

Motif DE_36h DE_36h-NR4A1_MA1112.3 8 bp overlap

NR4A2 1 dataset

Motif DE_36h DE_36h-NR4A2_MA0160.3 8 bp overlap

Nkx3-2 1 dataset

Motif DE_36h DE_36h-Nkx3-2_MA0122.4 10 bp overlap

PDX1 4 datasets

ChIP hESC GSE58685.PDX1.hESC 183 bp overlap

ChIP hiPSC GSE125768.PDX1.hiPSC 445 bp overlap

ChIP hiPSC_derived_PPs GSE106949.PDX1.hiPSC_derived_PPs 355 bp overlap

ChIP pancreatic-progenitor GSE117136.PDX1.pancreatic-progenitor 487 bp overlap

PKNOX1 2 datasets

ChIP GM12878 ENCFF589FCY 437 bp overlap

ChIP GM12878 ENCSR711XNY.PKNOX1.GM12878 327 bp overlap

Pax7 1 dataset

Motif DE_36h DE_36h-Pax7_MA0680.3 10 bp overlap

Prdm4 1 dataset

Motif DE_36h DE_36h-Prdm4_MA1647.3 11 bp overlap

SMAD2 2 datasets

Motif DE_36h DE_36h-SMAD2_MA1964.2 6 bp overlap

ChIP endoderm GSE29422.SMAD2.endoderm 190 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 502 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 569 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 489 bp overlap

SMAD2_3 4 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 435 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 541 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 514 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 365 bp overlap

SMARCA4 1 dataset

ChIP hiPSC GSE124903.SMARCA4.hiPSC 279 bp overlap

SOX10 1 dataset

Motif DE_36h DE_36h-SOX10_MA0442.3 6 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 404 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 458 bp overlap

Sox17 1 dataset

Motif DE_36h DE_36h-Sox17_MA0078.3 10 bp overlap

T 2 datasets

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 397 bp overlap

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 429 bp overlap

TBX21 2 datasets

ChIP GM12878 ENCFF951HUW 485 bp overlap

ChIP GM12878 ENCSR739IHN.TBX21.GM12878 549 bp overlap

TEAD4 1 dataset

Motif DE_36h DE_36h-TEAD4_MA0809.3 8 bp overlap

ZNF410 1 dataset

Motif DE_36h DE_36h-ZNF410_MA0752.2 16 bp overlap

ZNF524 1 dataset

Motif DE_36h DE_36h-ZNF524_MA2096.1 9 bp overlap

ZNF75A 1 dataset

Motif DE_36h DE_36h-ZNF75A_MA2097.1 12 bp overlap

Zfp809 1 dataset

Motif DE_36h DE_36h-Zfp809_MA2125.1 9 bp overlap

Genome Browser