chr3 : 132,295,035 – 132,295,625

590 bp 86 TFs 1 linked gene

This 590 bp open chromatin element is linked to CPNE4 and is bound by 86 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
CPNE4		9.6 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

86 transcription factors

ALX3 1 dataset

Motif DE_72h DE_72h-ALX3_MA0634.2 6 bp overlap

Arx 1 dataset

Motif DE_72h DE_72h-Arx_MA0874.2 10 bp overlap

Cebpa 2 datasets

ChIP BLaER1 ENCFF031ISE 251 bp overlap

ChIP BLaER1 ENCFF364PUR 299 bp overlap

DRGX 1 dataset

Motif DE_72h DE_72h-DRGX_MA1481.2 6 bp overlap

Dlx2 1 dataset

Motif DE_72h DE_72h-Dlx2_MA0885.3 8 bp overlap

Dlx5 1 dataset

Motif DE_72h DE_72h-Dlx5_MA1476.3 8 bp overlap

EMX1 1 dataset

Motif DE_72h DE_72h-EMX1_MA0612.3 6 bp overlap

EMX2 1 dataset

Motif DE_72h DE_72h-EMX2_MA0886.2 6 bp overlap

EN1 1 dataset

Motif DE_72h DE_72h-EN1_MA0027.3 6 bp overlap

EN2 1 dataset

Motif DE_72h DE_72h-EN2_MA0642.3 7 bp overlap

ERF::FOXI1 1 dataset

Motif DE_72h DE_72h-ERFFOXI1_MA1935.2 10 bp overlap

ERF::FOXO1 1 dataset

Motif DE_72h DE_72h-ERFFOXO1_MA1936.2 12 bp overlap

ESX1 1 dataset

Motif DE_72h DE_72h-ESX1_MA0644.3 7 bp overlap

ETV2::FOXI1 1 dataset

Motif DE_72h DE_72h-ETV2FOXI1_MA1942.2 11 bp overlap

ETV5::FOXI1 1 dataset

Motif DE_72h DE_72h-ETV5FOXI1_MA1946.2 12 bp overlap

ETV5::FOXO1 1 dataset

Motif DE_72h DE_72h-ETV5FOXO1_MA1947.2 10 bp overlap

EVX1 1 dataset

Motif DE_72h DE_72h-EVX1_MA0887.2 6 bp overlap

EVX2 1 dataset

Motif DE_72h DE_72h-EVX2_MA0888.2 6 bp overlap

FLI1::FOXI1 1 dataset

Motif DE_72h DE_72h-FLI1FOXI1_MA1950.2 11 bp overlap

FOXA2 1 dataset

ChIP DE DE-FOXA2-1 392 bp overlap

FOXO1::ELF1 1 dataset

Motif DE_72h DE_72h-FOXO1ELF1_MA1953.2 13 bp overlap

FOXO1::ELK1 1 dataset

Motif DE_72h DE_72h-FOXO1ELK1_MA1954.2 13 bp overlap

FOXO1::FLI1 1 dataset

Motif DE_72h DE_72h-FOXO1FLI1_MA1956.2 13 bp overlap

GATA1 4 datasets

ChIP CD34_ERYTH_BIO GSE29194.GATA1.CD34_ERYTH_BIO 109 bp overlap

ChIP CD34_ERYTH_BMP GSE29194.GATA1.CD34_ERYTH_BMP 177 bp overlap

ChIP erythroblast ENCFF867JAR 395 bp overlap

ChIP erythroblast ENCSR000EXP.GATA1.erythroblast 208 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 590 bp overlap

ChIP DE DE-GATA4-2 590 bp overlap

GATA6 3 datasets

ChIP DE DE-GATA6-1 515 bp overlap

ChIP DE DE-GATA6-2 577 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 506 bp overlap

GBX1 1 dataset

Motif DE_72h DE_72h-GBX1_MA0889.2 7 bp overlap

GRHL2 1 dataset

Motif DE_72h DE_72h-GRHL2_MA1105.3 8 bp overlap

GSX1 1 dataset

Motif DE_72h DE_72h-GSX1_MA0892.2 6 bp overlap

GSX2 1 dataset

Motif DE_72h DE_72h-GSX2_MA0893.3 7 bp overlap

HOXA1 1 dataset

Motif DE_72h DE_72h-HOXA1_MA1495.2 6 bp overlap

HOXA2 1 dataset

Motif DE_72h DE_72h-HOXA2_MA0900.3 6 bp overlap

HOXA3 1 dataset

Motif DE_72h DE_72h-HOXA3_MA2119.1 7 bp overlap

HOXA5 1 dataset

Motif DE_72h DE_72h-HOXA5_MA0158.2 8 bp overlap

HOXA6 1 dataset

Motif DE_72h DE_72h-HOXA6_MA1497.2 7 bp overlap

HOXB1 1 dataset

Motif DE_72h DE_72h-HOXB1_MA2093.1 7 bp overlap

HOXB2 1 dataset

Motif DE_72h DE_72h-HOXB2_MA0902.3 6 bp overlap

HOXB3 1 dataset

Motif DE_72h DE_72h-HOXB3_MA0903.2 6 bp overlap

HOXB5 1 dataset

Motif DE_72h DE_72h-HOXB5_MA0904.3 6 bp overlap

HOXB6 1 dataset

Motif DE_72h DE_72h-HOXB6_MA1500.2 7 bp overlap

HOXB7 1 dataset

Motif DE_72h DE_72h-HOXB7_MA1501.2 7 bp overlap

HOXB8 1 dataset

Motif DE_72h DE_72h-HOXB8_MA1502.2 7 bp overlap

HOXC8 1 dataset

Motif DE_72h DE_72h-HOXC8_MA1505.2 6 bp overlap

HOXD3 1 dataset

Motif DE_72h DE_72h-HOXD3_MA0912.2 8 bp overlap

HOXD8 1 dataset

Motif DE_72h DE_72h-HOXD8_MA0910.3 7 bp overlap

ISX 1 dataset

Motif DE_72h DE_72h-ISX_MA0654.2 6 bp overlap

LBX1 1 dataset

Motif DE_72h DE_72h-LBX1_MA0618.2 7 bp overlap

LDB1 1 dataset

ChIP HEP GSE52637.LDB1.HEP 171 bp overlap

LHX5 1 dataset

Motif DE_72h DE_72h-LHX5_MA1519.2 7 bp overlap

LHX6 1 dataset

Motif DE_72h DE_72h-LHX6_MA0658.2 8 bp overlap

LHX9 1 dataset

Motif DE_72h DE_72h-LHX9_MA0701.3 7 bp overlap

LMX1A 1 dataset

Motif DE_72h DE_72h-LMX1A_MA0702.3 7 bp overlap

LMX1B 1 dataset

Motif DE_72h DE_72h-LMX1B_MA0703.3 8 bp overlap

Lhx4 1 dataset

Motif DE_72h DE_72h-Lhx4_MA0704.2 6 bp overlap

Lhx8 1 dataset

Motif DE_72h DE_72h-Lhx8_MA0705.2 6 bp overlap

MEOX1 1 dataset

Motif DE_72h DE_72h-MEOX1_MA0661.2 7 bp overlap

MEOX2 1 dataset

Motif DE_72h DE_72h-MEOX2_MA0706.2 7 bp overlap

MIXL1 1 dataset

Motif DE_72h DE_72h-MIXL1_MA0662.2 6 bp overlap

MNX1 1 dataset

Motif DE_72h DE_72h-MNX1_MA0707.3 6 bp overlap

NKX6-2 1 dataset

Motif DE_72h DE_72h-NKX6-2_MA0675.2 6 bp overlap

NOTO 1 dataset

Motif DE_72h DE_72h-NOTO_MA0710.2 7 bp overlap

PAX4 1 dataset

Motif DE_72h DE_72h-PAX4_MA0068.2 8 bp overlap

PDX1 1 dataset

Motif DE_72h DE_72h-PDX1_MA0132.3 6 bp overlap

POU6F1 1 dataset

Motif DE_72h DE_72h-POU6F1_MA0628.2 6 bp overlap

PRRX1 1 dataset

Motif DE_72h DE_72h-PRRX1_MA0716.2 6 bp overlap

PRRX2 1 dataset

Motif DE_72h DE_72h-PRRX2_MA0075.4 7 bp overlap

RAX2 1 dataset

Motif DE_72h DE_72h-RAX2_MA0717.2 6 bp overlap

SHOX 1 dataset

Motif DE_72h DE_72h-SHOX_MA0630.2 6 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 254 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 490 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 468 bp overlap

SOX12 1 dataset

Motif DE_72h DE_72h-SOX12_MA1561.2 10 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 369 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 572 bp overlap

STAT1_pS727 1 dataset

ChIP SET-2 GSE100566.STAT1_pS727.SET-2 290 bp overlap

Shox2 1 dataset

Motif DE_72h DE_72h-Shox2_MA0720.2 6 bp overlap

Sox11 1 dataset

Motif DE_72h DE_72h-Sox11_MA0869.3 8 bp overlap

TAL1 1 dataset

ChIP ProEs GSE59087.TAL1.ProEs 179 bp overlap

TLX2 1 dataset

Motif DE_72h DE_72h-TLX2_MA1577.2 6 bp overlap

UNCX 1 dataset

Motif DE_72h DE_72h-UNCX_MA0721.2 6 bp overlap

VAX1 1 dataset

Motif DE_72h DE_72h-VAX1_MA0722.2 7 bp overlap

VAX2 1 dataset

Motif DE_72h DE_72h-VAX2_MA0723.3 6 bp overlap

VSX1 1 dataset

Motif DE_72h DE_72h-VSX1_MA0725.2 7 bp overlap

VSX2 1 dataset

Motif DE_72h DE_72h-VSX2_MA0726.2 7 bp overlap

ZBTB7A 1 dataset

ChIP HUDEP-2 GSE103445.ZBTB7A.HUDEP-2 103 bp overlap

ZNF677 1 dataset

Motif DE_72h DE_72h-ZNF677_MA2101.1 12 bp overlap

ZSCAN21 1 dataset

Motif DE_72h DE_72h-ZSCAN21_MA2336.1 7 bp overlap