chr3 : 89,117,432 – 89,117,900
468 bp 43 TFs 1 linked gene
This 468 bp open chromatin element is linked to EPHA3 and is bound by 43 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
EPHA3 9.8 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr3:89,112,432 – 89,122,900
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
43 transcription factors
Source
Cell type
CRX 2 datasets
ChIP retina_Hu3 GSE137311.CRX.retina_Hu3 165 bp overlap
ChIP retina_Hu6 GSE137311.CRX.retina_Hu6 243 bp overlap
Crx 4 datasets
Motif DE_48h DE_48h-Crx_MA0467.3 6 bp overlap
Motif DE_48h DE_48h-Crx_MA0467.3 6 bp overlap
Motif DE_60h DE_60h-Crx_MA0467.3 6 bp overlap
Motif DE_60h DE_60h-Crx_MA0467.3 6 bp overlap
DPRX 4 datasets
Motif DE_48h DE_48h-DPRX_MA1480.2 9 bp overlap
Motif DE_48h DE_48h-DPRX_MA1480.2 9 bp overlap
Motif DE_60h DE_60h-DPRX_MA1480.2 9 bp overlap
Motif DE_60h DE_60h-DPRX_MA1480.2 9 bp overlap
EBF1 2 datasets
Motif DE_48h DE_48h-EBF1_MA0154.5 11 bp overlap
Motif DE_60h DE_60h-EBF1_MA0154.5 11 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 468 bp overlap
ERG 1 dataset
ChIP VCaP GSE49091.ERG.VCaP 66 bp overlap
Ebf4 2 datasets
Motif DE_48h DE_48h-Ebf4_MA2122.1 11 bp overlap
Motif DE_60h DE_60h-Ebf4_MA2122.1 11 bp overlap
Erg 1 dataset
Motif DE_48h DE_48h-Erg_MA0474.4 10 bp overlap
FOXA1 1 dataset
ChIP LAPC-4_TFS_p358fs-V5 GSE123618.FOXA1.LAPC-4_TFS_p358fs-V5 217 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 468 bp overlap
ChIP DE DE-FOXA2-2 462 bp overlap
FOXH1 2 datasets
Motif DE_48h DE_48h-FOXH1_MA0479.2 8 bp overlap
Motif DE_60h DE_60h-FOXH1_MA0479.2 8 bp overlap
FOXJ2::ELF1 1 dataset
Motif DE_48h DE_48h-FOXJ2ELF1_MA1952.2 11 bp overlap
GABPA 1 dataset
Motif DE_48h DE_48h-GABPA_MA0062.4 10 bp overlap
GATA4 5 datasets
ChIP DE DE-GATA4-1 468 bp overlap
ChIP DE DE-GATA4-2 468 bp overlap
ChIP foregut GSE117136.GATA4.foregut 343 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 468 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 402 bp overlap
GATA6 11 datasets
ChIP DE DE-GATA6-1 468 bp overlap
ChIP DE DE-GATA6-2 468 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 456 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 468 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 468 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 468 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 468 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 468 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 468 bp overlap
ChIP foregut GSE117136.GATA6.foregut 279 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 275 bp overlap
GSC 4 datasets
Motif DE_48h DE_48h-GSC_MA0648.2 6 bp overlap
Motif DE_48h DE_48h-GSC_MA0648.2 6 bp overlap
Motif DE_60h DE_60h-GSC_MA0648.2 6 bp overlap
Motif DE_60h DE_60h-GSC_MA0648.2 6 bp overlap
GSC2 4 datasets
Motif DE_48h DE_48h-GSC2_MA0891.2 6 bp overlap
Motif DE_48h DE_48h-GSC2_MA0891.2 6 bp overlap
Motif DE_60h DE_60h-GSC2_MA0891.2 6 bp overlap
Motif DE_60h DE_60h-GSC2_MA0891.2 6 bp overlap
IKZF1 1 dataset
Motif DE_48h DE_48h-IKZF1_MA1508.2 8 bp overlap
MEF2D 2 datasets
ChIP retina_Hu13 GSE137311.MEF2D.retina_Hu13 296 bp overlap
ChIP retina_Hu25 GSE137311.MEF2D.retina_Hu25 221 bp overlap
MSANTD3 1 dataset
Motif DE_48h DE_48h-MSANTD3_MA1523.2 7 bp overlap
MXI1 2 datasets
Motif DE_48h DE_48h-MXI1_MA1108.3 6 bp overlap
Motif DE_60h DE_60h-MXI1_MA1108.3 6 bp overlap
NEUROD1 1 dataset
ChIP D341-Med_shNEUROD1-1154 GSE92582.NEUROD1.D341-Med_shNEUROD1-1154 180 bp overlap
NKX2-2 1 dataset
Motif DE_48h DE_48h-NKX2-2_MA1645.2 8 bp overlap
ONECUT1 1 dataset
ChIP pancreatic-progenitor_PP1 GSE104840.ONECUT1.pancreatic-progenitor_PP1 464 bp overlap
OTX1 4 datasets
Motif DE_48h DE_48h-OTX1_MA0711.2 6 bp overlap
Motif DE_48h DE_48h-OTX1_MA0711.2 6 bp overlap
Motif DE_60h DE_60h-OTX1_MA0711.2 6 bp overlap
Motif DE_60h DE_60h-OTX1_MA0711.2 6 bp overlap
OTX2 1 dataset
ChIP retina_Hu7 GSE137311.OTX2.retina_Hu7 305 bp overlap
PITX1 4 datasets
Motif DE_48h DE_48h-PITX1_MA0682.3 6 bp overlap
Motif DE_48h DE_48h-PITX1_MA0682.3 6 bp overlap
Motif DE_60h DE_60h-PITX1_MA0682.3 6 bp overlap
Motif DE_60h DE_60h-PITX1_MA0682.3 6 bp overlap
PITX2 2 datasets
Motif DE_48h DE_48h-PITX2_MA1547.2 8 bp overlap
Motif DE_60h DE_60h-PITX2_MA1547.2 8 bp overlap
PITX3 4 datasets
Motif DE_48h DE_48h-PITX3_MA0714.2 6 bp overlap
Motif DE_48h DE_48h-PITX3_MA0714.2 6 bp overlap
Motif DE_60h DE_60h-PITX3_MA0714.2 6 bp overlap
Motif DE_60h DE_60h-PITX3_MA0714.2 6 bp overlap
PRDM6 3 datasets
ChIP HEK293 ENCFF283AJL 210 bp overlap
ChIP HEK293 ENCSR892QHR.PRDM6.HEK293 468 bp overlap
ChIP HEK293 GSE76494.PRDM6.HEK293 148 bp overlap
RBPJ 1 dataset
ChIP GSC8-11_12d-das GSE74557.RBPJ.GSC8-11_12d-das 163 bp overlap
RHOXF1 4 datasets
Motif DE_48h DE_48h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_48h DE_48h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_60h DE_60h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_60h DE_60h-RHOXF1_MA0719.2 6 bp overlap
RING1 1 dataset
ChIP SYO-1_shRING1A-B GSE139053.RING1.SYO-1_shRING1A-B 136 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 386 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 468 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 370 bp overlap
SMAD2_3 3 datasets
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 468 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 357 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 468 bp overlap
SMARCA4 5 datasets
ChIP 22Rv1 GSE115615.SMARCA4.22Rv1 198 bp overlap
ChIP 501-mel_SHCTR GSE61965.SMARCA4.501-mel_SHCTR 117 bp overlap
ChIP Aska-SS GSE108025.SMARCA4.Aska-SS 165 bp overlap
ChIP Aska-SS GSE108025.SMARCA4.Aska-SS 137 bp overlap
ChIP hiPSC GSE124903.SMARCA4.hiPSC 338 bp overlap
SMARCC1 1 dataset
ChIP Aska-SS GSE108025.SMARCC1.Aska-SS 468 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 407 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 341 bp overlap
SS18 1 dataset
ChIP Aska-SS_BAF47KO1 GSE108025.SS18.Aska-SS_BAF47KO1 323 bp overlap
ZNF16 1 dataset
Motif DE_60h DE_60h-ZNF16_MA1654.2 21 bp overlap
ZNF354C 2 datasets
Motif DE_48h DE_48h-ZNF354C_MA0130.1 6 bp overlap
Motif DE_60h DE_60h-ZNF354C_MA0130.1 6 bp overlap
ZNF528 1 dataset
Motif DE_60h DE_60h-ZNF528_MA1597.1 17 bp overlap
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