Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

40 transcription factors

BRD4 3 datasets

ChIP Kelly_sensitive GSE103030.BRD4.Kelly_sensitive 218 bp overlap

ChIP MOLM-14_CA25 GSE65138.BRD4.MOLM-14_CA25 435 bp overlap

ChIP MV4-11_DMSO GSE71776.BRD4.MV4-11_DMSO 397 bp overlap

CDK8 1 dataset

ChIP MOLM-14_IBET GSE65138.CDK8.MOLM-14_IBET 64 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF093OYK 251 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 274 bp overlap

ESRRG 1 dataset

ChIP cardiomyocyte GSE113760.ESRRG.cardiomyocyte 271 bp overlap

FOXA1 2 datasets

ChIP LNCaP-abl GSE63034.FOXA1.LNCaP-abl 98 bp overlap

ChIP LNCaP_F266S_shFOXA1 GSE128883.FOXA1.LNCaP_F266S_shFOXA1 159 bp overlap

FOXA2 3 datasets

ChIP Caco-2 GSE66218.FOXA2.Caco-2 202 bp overlap

ChIP DE DE-FOXA2-1 389 bp overlap

ChIP DE DE-FOXA2-2 495 bp overlap

FOXL2 4 datasets

ChIP HGrC1_C134W-TGF GSE138496.FOXL2.HGrC1_C134W-TGF 245 bp overlap

ChIP HGrC1_C134W-TGF_parental GSE138496.FOXL2.HGrC1_C134W-TGF_parental 163 bp overlap

ChIP KGN_1512 GSE138496.FOXL2.KGN_1512 152 bp overlap

ChIP KGN_1513 GSE138496.FOXL2.KGN_1513 179 bp overlap

GATA1 2 datasets

ChIP HUDEP-2_30min GSE104676.GATA1.HUDEP-2_30min 80 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 138 bp overlap

GATA2 3 datasets

Motif DE_48h DE_48h-GATA2_MA0036.4 7 bp overlap

Motif DE_60h DE_60h-GATA2_MA0036.4 7 bp overlap

ChIP TF1 GSE73207.GATA2.TF1 291 bp overlap

GATA3 1 dataset

ChIP Kelly GSE65664.GATA3.Kelly 189 bp overlap

GATA4 9 datasets

ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.GATA4.BJ1-hTERT_FOXA2_GATA4_Coexp 207 bp overlap

ChIP DE DE-GATA4-1 449 bp overlap

ChIP DE DE-GATA4-2 495 bp overlap

Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap

Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap

ChIP Hep-G2 GSE135714.GATA4.Hep-G2 430 bp overlap

ChIP foregut GSE117136.GATA4.foregut 389 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 455 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 314 bp overlap

GATA5 2 datasets

Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap

Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap

GATA6 15 datasets

ChIP AGS GSE51705.GATA6.AGS 231 bp overlap

ChIP DE DE-GATA6-1 479 bp overlap

ChIP DE DE-GATA6-2 495 bp overlap

Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap

Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 249 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 332 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 391 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 389 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 280 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 447 bp overlap

ChIP foregut GSE117136.GATA6.foregut 359 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 376 bp overlap

ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 383 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 276 bp overlap

Gata3 2 datasets

Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap

Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap

IRF5 1 dataset

Motif DE_60h DE_60h-IRF5_MA1420.1 14 bp overlap

MYC 1 dataset

ChIP HeLa-S3 ENCSR000EZD.MYC.HeLa-S3 169 bp overlap

NEUROD1 1 dataset

ChIP D283-Med GSE92582.NEUROD1.D283-Med 186 bp overlap

NFIC::TLX1 2 datasets

Motif DE_48h DE_48h-NFICTLX1_MA0119.1 14 bp overlap

Motif DE_60h DE_60h-NFICTLX1_MA0119.1 14 bp overlap

NUTM1 1 dataset

ChIP NMC24335 GSE96775.NUTM1.NMC24335 145 bp overlap

PRDM6 2 datasets

ChIP HEK293 ENCFF283AJL 266 bp overlap

ChIP HEK293 ENCSR892QHR.PRDM6.HEK293 180 bp overlap

RFX1 2 datasets

Motif DE_48h DE_48h-RFX1_MA0509.3 16 bp overlap

Motif DE_60h DE_60h-RFX1_MA0509.3 16 bp overlap

RFX2 2 datasets

Motif DE_48h DE_48h-RFX2_MA0600.3 14 bp overlap

Motif DE_60h DE_60h-RFX2_MA0600.3 14 bp overlap

RFX3 2 datasets

Motif DE_48h DE_48h-RFX3_MA0798.3 16 bp overlap

Motif DE_60h DE_60h-RFX3_MA0798.3 16 bp overlap

RFX5 2 datasets

Motif DE_48h DE_48h-RFX5_MA0510.3 14 bp overlap

Motif DE_60h DE_60h-RFX5_MA0510.3 14 bp overlap

RFX7 2 datasets

Motif DE_48h DE_48h-RFX7_MA1554.2 8 bp overlap

Motif DE_60h DE_60h-RFX7_MA1554.2 8 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 220 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 339 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 426 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 407 bp overlap

SMAD4 1 dataset

ChIP endoderm GSE29422.SMAD4.endoderm 230 bp overlap

SMARCA4 1 dataset

ChIP HS-SY-2_HA-tagged GSE108926.SMARCA4.HS-SY-2_HA-tagged 495 bp overlap

Smad4 1 dataset

Motif DE_60h DE_60h-Smad4_MA1153.2 7 bp overlap

TAL1 1 dataset

ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 158 bp overlap

TBX5 1 dataset

ChIP hiPSC GSE81585.TBX5.hiPSC 262 bp overlap

TEAD3 1 dataset

ChIP HepG2 ENCFF054UUL 371 bp overlap

TLE3 1 dataset

ChIP LNCaP GSE94682.TLE3.LNCaP 150 bp overlap

TRPS1 2 datasets

Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap

Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap

ZNF282 1 dataset

Motif DE_60h DE_60h-ZNF282_MA1154.2 15 bp overlap

ZNF3 1 dataset

ChIP Hep-G2 ENCSR182QWU.ZNF3.Hep-G2 166 bp overlap

ZXDB 2 datasets

ChIP HEK293 ENCFF835SGA 459 bp overlap

ChIP HEK293 ENCSR559IOZ.ZXDB.HEK293 352 bp overlap

Genome Browser