Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

47 transcription factors

BCL6 3 datasets

Motif DE_48h DE_48h-BCL6_MA0463.3 13 bp overlap

Motif DE_60h DE_60h-BCL6_MA0463.3 13 bp overlap

Motif DE_72h DE_72h-BCL6_MA0463.3 13 bp overlap

CTCF 1 dataset

ChIP endodermal cell ENCFF471YCZ 309 bp overlap

EBF1 2 datasets

Motif DE_48h DE_48h-EBF1_MA0154.5 11 bp overlap

Motif DE_60h DE_60h-EBF1_MA0154.5 11 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 263 bp overlap

ERF::FOXI1 3 datasets

Motif DE_48h DE_48h-ERFFOXI1_MA1935.2 10 bp overlap

Motif DE_60h DE_60h-ERFFOXI1_MA1935.2 10 bp overlap

Motif DE_72h DE_72h-ERFFOXI1_MA1935.2 10 bp overlap

ETV5::FOXI1 3 datasets

Motif DE_48h DE_48h-ETV5FOXI1_MA1946.2 12 bp overlap

Motif DE_60h DE_60h-ETV5FOXI1_MA1946.2 12 bp overlap

Motif DE_72h DE_72h-ETV5FOXI1_MA1946.2 12 bp overlap

Ebf4 2 datasets

Motif DE_48h DE_48h-Ebf4_MA2122.1 11 bp overlap

Motif DE_60h DE_60h-Ebf4_MA2122.1 11 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 299 bp overlap

ChIP DE DE-FOXA2-2 454 bp overlap

FOXO1::ELK1 3 datasets

Motif DE_48h DE_48h-FOXO1ELK1_MA1954.2 13 bp overlap

Motif DE_60h DE_60h-FOXO1ELK1_MA1954.2 13 bp overlap

Motif DE_72h DE_72h-FOXO1ELK1_MA1954.2 13 bp overlap

GATA4 3 datasets

ChIP DE DE-GATA4-1 496 bp overlap

ChIP DE DE-GATA4-2 496 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 264 bp overlap

GATA6 5 datasets

ChIP DE DE-GATA6-1 438 bp overlap

ChIP DE DE-GATA6-2 496 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 491 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 261 bp overlap

ChIP foregut GSE117136.GATA6.foregut 315 bp overlap

HNF4A 1 dataset

Motif DE_60h DE_60h-HNF4A_MA1494.2 14 bp overlap

IKZF1 3 datasets

Motif DE_48h DE_48h-IKZF1_MA1508.2 8 bp overlap

Motif DE_60h DE_60h-IKZF1_MA1508.2 8 bp overlap

Motif DE_72h DE_72h-IKZF1_MA1508.2 8 bp overlap

IKZF2 3 datasets

Motif DE_48h DE_48h-IKZF2_MA2326.1 6 bp overlap

Motif DE_60h DE_60h-IKZF2_MA2326.1 6 bp overlap

Motif DE_72h DE_72h-IKZF2_MA2326.1 6 bp overlap

MYB 3 datasets

Motif DE_48h DE_48h-MYB_MA0100.4 6 bp overlap

Motif DE_60h DE_60h-MYB_MA0100.4 6 bp overlap

Motif DE_72h DE_72h-MYB_MA0100.4 6 bp overlap

Mecom 1 dataset

Motif DE_60h DE_60h-Mecom_MA0029.2 11 bp overlap

NFATC3 1 dataset

Motif DE_60h DE_60h-NFATC3_MA0625.3 6 bp overlap

Nfatc1 1 dataset

Motif DE_60h DE_60h-Nfatc1_MA0624.3 6 bp overlap

PPARD 1 dataset

Motif DE_60h DE_60h-PPARD_MA1550.2 14 bp overlap

PRDM9 1 dataset

Motif DE_60h DE_60h-PRDM9_MA1723.2 20 bp overlap

Prdm4 3 datasets

Motif DE_48h DE_48h-Prdm4_MA1647.3 11 bp overlap

Motif DE_60h DE_60h-Prdm4_MA1647.3 11 bp overlap

Motif DE_72h DE_72h-Prdm4_MA1647.3 11 bp overlap

RFX4 3 datasets

Motif DE_48h DE_48h-RFX4_MA0799.3 13 bp overlap

Motif DE_60h DE_60h-RFX4_MA0799.3 13 bp overlap

Motif DE_72h DE_72h-RFX4_MA0799.3 13 bp overlap

Rarb 1 dataset

Motif DE_60h DE_60h-Rarb_MA0857.1 16 bp overlap

Rfx6 3 datasets

Motif DE_48h DE_48h-Rfx6_MA1724.2 9 bp overlap

Motif DE_60h DE_60h-Rfx6_MA1724.2 9 bp overlap

Motif DE_72h DE_72h-Rfx6_MA1724.2 9 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 304 bp overlap

SMAD2_3 1 dataset

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 253 bp overlap

SOX10 1 dataset

Motif DE_60h DE_60h-SOX10_MA0442.3 6 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 210 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 462 bp overlap

SOX18 1 dataset

Motif DE_48h DE_48h-SOX18_MA1563.2 8 bp overlap

SOX4 1 dataset

Motif DE_60h DE_60h-SOX4_MA0867.3 8 bp overlap

SOX9 1 dataset

Motif DE_48h DE_48h-SOX9_MA0077.2 8 bp overlap

SP5 2 datasets

Motif DE_48h DE_48h-SP5_MA1965.2 6 bp overlap

Motif DE_60h DE_60h-SP5_MA1965.2 6 bp overlap

Sox5 1 dataset

Motif DE_48h DE_48h-Sox5_MA0087.3 8 bp overlap

Sox6 1 dataset

Motif DE_60h DE_60h-Sox6_MA0515.1 10 bp overlap

Spi1 3 datasets

Motif DE_48h DE_48h-Spi1_MA0080.7 13 bp overlap

Motif DE_60h DE_60h-Spi1_MA0080.7 13 bp overlap

Motif DE_72h DE_72h-Spi1_MA0080.7 13 bp overlap

TAL1 2 datasets

ChIP K-562_dCas9-KRAB GSE132212.TAL1.K-562_dCas9-KRAB 179 bp overlap

ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 148 bp overlap

TFAP2A 5 datasets

Motif DE_48h DE_48h-TFAP2A_MA0003.5 9 bp overlap

Motif DE_48h DE_48h-TFAP2A_MA0810.2 11 bp overlap

Motif DE_60h DE_60h-TFAP2A_MA0003.5 9 bp overlap

Motif DE_60h DE_60h-TFAP2A_MA0810.2 11 bp overlap

Motif DE_72h DE_72h-TFAP2A_MA0003.5 9 bp overlap

TFAP2B 6 datasets

Motif DE_48h DE_48h-TFAP2B_MA0811.2 11 bp overlap

Motif DE_48h DE_48h-TFAP2B_MA0812.2 9 bp overlap

Motif DE_60h DE_60h-TFAP2B_MA0811.2 11 bp overlap

Motif DE_60h DE_60h-TFAP2B_MA0812.2 9 bp overlap

Motif DE_72h DE_72h-TFAP2B_MA0811.2 11 bp overlap

Motif DE_72h DE_72h-TFAP2B_MA0812.2 9 bp overlap

TFAP2C 6 datasets

Motif DE_48h DE_48h-TFAP2C_MA0524.3 11 bp overlap

Motif DE_48h DE_48h-TFAP2C_MA0814.3 9 bp overlap

Motif DE_60h DE_60h-TFAP2C_MA0524.3 11 bp overlap

Motif DE_60h DE_60h-TFAP2C_MA0814.3 9 bp overlap

Motif DE_72h DE_72h-TFAP2C_MA0524.3 11 bp overlap

Motif DE_72h DE_72h-TFAP2C_MA0814.3 9 bp overlap

TFAP2E 3 datasets

Motif DE_48h DE_48h-TFAP2E_MA1569.2 9 bp overlap

Motif DE_60h DE_60h-TFAP2E_MA1569.2 9 bp overlap

Motif DE_72h DE_72h-TFAP2E_MA1569.2 9 bp overlap

THRB 1 dataset

Motif DE_60h DE_60h-THRB_MA1574.2 13 bp overlap

ZNF213 1 dataset

Motif DE_60h DE_60h-ZNF213_MA2121.1 12 bp overlap

ZNF528 2 datasets

Motif DE_48h DE_48h-ZNF528_MA1597.1 17 bp overlap

Motif DE_60h DE_60h-ZNF528_MA1597.1 17 bp overlap

ZNF549 1 dataset

Motif DE_60h DE_60h-ZNF549_MA1728.2 8 bp overlap

ZNF766 1 dataset

Motif DE_60h DE_60h-ZNF766_MA2098.1 9 bp overlap

Zfp335 1 dataset

Motif DE_60h DE_60h-Zfp335_MA2002.2 7 bp overlap

Genome Browser