Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

55 transcription factors

BARX1 1 dataset

Motif DE_48h DE_48h-BARX1_MA0875.2 6 bp overlap

BSX 1 dataset

Motif DE_48h DE_48h-BSX_MA0876.2 6 bp overlap

CBX8 1 dataset

ChIP K-562 ENCSR000ATW.CBX8.K-562 242 bp overlap

DLX1 1 dataset

Motif DE_48h DE_48h-DLX1_MA0879.3 6 bp overlap

DLX6 1 dataset

Motif DE_48h DE_48h-DLX6_MA0882.2 6 bp overlap

Dlx2 1 dataset

Motif DE_48h DE_48h-Dlx2_MA0885.3 8 bp overlap

Dlx3 1 dataset

Motif DE_48h DE_48h-Dlx3_MA0880.2 6 bp overlap

Dlx4 1 dataset

Motif DE_48h DE_48h-Dlx4_MA0881.2 6 bp overlap

Dlx5 1 dataset

Motif DE_48h DE_48h-Dlx5_MA1476.3 8 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 318 bp overlap

ESR1 1 dataset

ChIP T-47D_D538G_E2 GSE148277.ESR1.T-47D_D538G_E2 79 bp overlap

FOXA1 4 datasets

ChIP HEK293_r261g_TFS GSE123618.FOXA1.HEK293_r261g_TFS 90 bp overlap

ChIP MCF-7-TAMR-1_4OH-Tam GSE75201.FOXA1.MCF-7-TAMR-1_4OH-Tam 95 bp overlap

ChIP T-47D_DMSO GSE84593.FOXA1.T-47D_DMSO 75 bp overlap

ChIP ZR751_DEX GSE72249.FOXA1.ZR751_DEX 96 bp overlap

FOXA2 4 datasets

ChIP DE DE-FOXA2-1 464 bp overlap

ChIP DE DE-FOXA2-2 464 bp overlap

ChIP KerCT GSE90454.FOXA2.KerCT 66 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.FOXA2.pancreatic-progenitor_PP1 97 bp overlap

FOXP1 1 dataset

ChIP Hep-G2 ENCSR369YUK.FOXP1.Hep-G2 62 bp overlap

GATA1 1 dataset

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 215 bp overlap

GATA4 5 datasets

ChIP DE DE-GATA4-1 464 bp overlap

ChIP DE DE-GATA4-2 464 bp overlap

ChIP foregut GSE117136.GATA4.foregut 403 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 407 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 280 bp overlap

GATA6 13 datasets

ChIP DE DE-GATA6-1 436 bp overlap

ChIP DE DE-GATA6-2 464 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 325 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 352 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 324 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 433 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 378 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 336 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 447 bp overlap

ChIP foregut GSE117136.GATA6.foregut 411 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 315 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 407 bp overlap

ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 455 bp overlap

GBX2 1 dataset

Motif DE_48h DE_48h-GBX2_MA0890.2 6 bp overlap

HESX1 1 dataset

Motif DE_48h DE_48h-HESX1_MA0894.2 6 bp overlap

HOXA5 1 dataset

Motif DE_48h DE_48h-HOXA5_MA0158.2 8 bp overlap

HOXA6 1 dataset

Motif DE_48h DE_48h-HOXA6_MA1497.2 7 bp overlap

HOXA7 1 dataset

Motif DE_48h DE_48h-HOXA7_MA1498.3 6 bp overlap

HOXB6 1 dataset

Motif DE_48h DE_48h-HOXB6_MA1500.2 7 bp overlap

HOXB7 1 dataset

Motif DE_48h DE_48h-HOXB7_MA1501.2 7 bp overlap

HOXB8 1 dataset

Motif DE_48h DE_48h-HOXB8_MA1502.2 7 bp overlap

HOXD8 1 dataset

Motif DE_48h DE_48h-HOXD8_MA0910.3 7 bp overlap

Hmx2 1 dataset

Motif DE_48h DE_48h-Hmx2_MA0897.2 15 bp overlap

KDM1A 2 datasets

ChIP pancreatic-progenitor_GT GSE104840.KDM1A.pancreatic-progenitor_GT 185 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.KDM1A.pancreatic-progenitor_PP1 160 bp overlap

LBX2 1 dataset

Motif DE_48h DE_48h-LBX2_MA0699.2 6 bp overlap

LHX2 1 dataset

Motif DE_48h DE_48h-LHX2_MA0700.3 6 bp overlap

MSANTD3 3 datasets

Motif DE_36h DE_36h-MSANTD3_MA1523.2 7 bp overlap

Motif DE_48h DE_48h-MSANTD3_MA1523.2 7 bp overlap

Motif DE_72h DE_72h-MSANTD3_MA1523.2 7 bp overlap

MSX1 1 dataset

Motif DE_48h DE_48h-MSX1_MA0666.3 6 bp overlap

MSX2 1 dataset

Motif DE_48h DE_48h-MSX2_MA0708.3 6 bp overlap

Msx3 1 dataset

Motif DE_48h DE_48h-Msx3_MA0709.2 6 bp overlap

NACC2 1 dataset

ChIP HepG2 ENCFF165SVB 406 bp overlap

NR2C1 3 datasets

Motif DE_36h DE_36h-NR2C1_MA1535.2 6 bp overlap

Motif DE_48h DE_48h-NR2C1_MA1535.2 6 bp overlap

Motif DE_72h DE_72h-NR2C1_MA1535.2 6 bp overlap

NR2C2 3 datasets

Motif DE_36h DE_36h-NR2C2_MA1536.2 6 bp overlap

Motif DE_48h DE_48h-NR2C2_MA1536.2 6 bp overlap

Motif DE_72h DE_72h-NR2C2_MA1536.2 6 bp overlap

NR3C1 1 dataset

ChIP T47D-A1-2_Dex GSE112491.NR3C1.T47D-A1-2_Dex 96 bp overlap

Nobox 1 dataset

Motif DE_48h DE_48h-Nobox_MA0125.2 6 bp overlap

Nr1H2 3 datasets

Motif DE_36h DE_36h-Nr1H2_MA1996.2 6 bp overlap

Motif DE_48h DE_48h-Nr1H2_MA1996.2 6 bp overlap

Motif DE_72h DE_72h-Nr1H2_MA1996.2 6 bp overlap

Nr1H4 3 datasets

Motif DE_36h DE_36h-Nr1H4_MA1110.3 6 bp overlap

Motif DE_48h DE_48h-Nr1H4_MA1110.3 6 bp overlap

Motif DE_72h DE_72h-Nr1H4_MA1110.3 6 bp overlap

Nr1h3 3 datasets

Motif DE_36h DE_36h-Nr1h3_MA2337.1 6 bp overlap

Motif DE_48h DE_48h-Nr1h3_MA2337.1 6 bp overlap

Motif DE_72h DE_72h-Nr1h3_MA2337.1 6 bp overlap

RAX 1 dataset

Motif DE_48h DE_48h-RAX_MA0718.2 6 bp overlap

RNF2 1 dataset

ChIP K-562 ENCSR820GND.RNF2.K-562 64 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 371 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 349 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 225 bp overlap

SMARCA4 1 dataset

ChIP K-562 ENCSR643VTW.SMARCA4.K-562 205 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 313 bp overlap

SOX21 1 dataset

Motif DE_48h DE_48h-SOX21_MA0866.1 15 bp overlap

T 1 dataset

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 207 bp overlap

TAL1 1 dataset

ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 219 bp overlap

TFAP2B 3 datasets

Motif DE_36h DE_36h-TFAP2B_MA0811.2 11 bp overlap

Motif DE_48h DE_48h-TFAP2B_MA0811.2 11 bp overlap

Motif DE_72h DE_72h-TFAP2B_MA0811.2 11 bp overlap

ZMYM4 1 dataset

ChIP HepG2 ENCFF567SQY 59 bp overlap

ZNF257 1 dataset

Motif DE_48h DE_48h-ZNF257_MA1710.2 10 bp overlap

ZNF766 1 dataset

Motif DE_36h DE_36h-ZNF766_MA2098.1 9 bp overlap

Genome Browser