chr2 : 162,832,627 – 162,833,033
406 bp 27 TFs 1 linked gene
This 406 bp open chromatin element is linked to KCNH7 and is bound by 27 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
KCNH7 5.7 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr2:162,827,627 – 162,838,033
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
27 transcription factors
Source
Cell type
AR 1 dataset
ChIP MCF-7 ERP001226.AR.MCF-7 237 bp overlap
ARID1A 3 datasets
ChIP MCF-7 GSE123284.ARID1A.MCF-7 181 bp overlap
ChIP MCF-7_4-hydroxytamoxifen GSE123284.ARID1A.MCF-7_4-hydroxytamoxifen 295 bp overlap
ChIP MCF-7_JQ1 GSE123284.ARID1A.MCF-7_JQ1 287 bp overlap
ARID2 2 datasets
ChIP MCF-7_parental GSE123284.ARID2.MCF-7_parental 226 bp overlap
ChIP MCF-7_parental_4-hydroxytamoxifen GSE123284.ARID2.MCF-7_parental_4-hydroxytamoxifen 206 bp overlap
BRD4 2 datasets
ChIP MCF-7_parental GSE123284.BRD4.MCF-7_parental 302 bp overlap
ChIP MCF-7_parental_4-hydroxytamoxifen GSE123284.BRD4.MCF-7_parental_4-hydroxytamoxifen 235 bp overlap
CREBBP 1 dataset
ChIP LS180 GSE39277.CREBBP.LS180 87 bp overlap
ESR1 90 datasets
ChIP MCF-7 GSE148277.ESR1.MCF-7 303 bp overlap
ChIP MCF-7 GSE68355.ESR1.MCF-7 289 bp overlap
ChIP MCF-7 GSE76893.ESR1.MCF-7 259 bp overlap
ChIP MCF-7 GSE41561.ESR1.MCF-7 237 bp overlap
ChIP MCF-7 GSE103023.ESR1.MCF-7 206 bp overlap
ChIP MCF-7 GSE95302.ESR1.MCF-7 197 bp overlap
ChIP MCF-7 GSE136673.ESR1.MCF-7 191 bp overlap
ChIP MCF-7 GSE117492.ESR1.MCF-7 140 bp overlap
ChIP MCF-7 GSE45822.ESR1.MCF-7 117 bp overlap
ChIP MCF-7 GSE48930.ESR1.MCF-7 114 bp overlap
ChIP MCF-7 GSE128445.ESR1.MCF-7 96 bp overlap
ChIP MCF-7-Luc_E2 GSE78284.ESR1.MCF-7-Luc_E2 93 bp overlap
ChIP MCF-7_1-6-HD GSE117492.ESR1.MCF-7_1-6-HD 131 bp overlap
ChIP MCF-7_4OH-Tam GSE117941.ESR1.MCF-7_4OH-Tam 233 bp overlap
ChIP MCF-7_ARID1A-KO GSE123284.ESR1.MCF-7_ARID1A-KO 406 bp overlap
ChIP MCF-7_ARID1A-KO_4-OHT GSE123284.ESR1.MCF-7_ARID1A-KO_4-OHT 406 bp overlap
ChIP MCF-7_ARID1A-KO_4-OHT_clone14 GSE123284.ESR1.MCF-7_ARID1A-KO_4-OHT_clone14 249 bp overlap
ChIP MCF-7_ARID1A-KO_clone14 GSE123284.ESR1.MCF-7_ARID1A-KO_clone14 261 bp overlap
ChIP MCF-7_AZD2014 GSE103023.ESR1.MCF-7_AZD2014 149 bp overlap
ChIP MCF-7_Abcam GSE128208.ESR1.MCF-7_Abcam 94 bp overlap
ChIP MCF-7_D538G_DMSO GSE148277.ESR1.MCF-7_D538G_DMSO 243 bp overlap
ChIP MCF-7_DMSO GSE133941.ESR1.MCF-7_DMSO 159 bp overlap
ChIP MCF-7_DMSO GSE125594.ESR1.MCF-7_DMSO 158 bp overlap
ChIP MCF-7_DMSO GSE148277.ESR1.MCF-7_DMSO 103 bp overlap
ChIP MCF-7_E2 ERP000209.ESR1.MCF-7_E2 195 bp overlap
ChIP MCF-7_E2 GSE72249.ESR1.MCF-7_E2 194 bp overlap
ChIP MCF-7_E2 GSE117941.ESR1.MCF-7_E2 194 bp overlap
ChIP MCF-7_E2 GSE68356.ESR1.MCF-7_E2 154 bp overlap
ChIP MCF-7_E2 ERP000901.ESR1.MCF-7_E2 58 bp overlap
ChIP MCF-7_E2 GSE59530.ESR1.MCF-7_E2 57 bp overlap
ChIP MCF-7_E2-10min-ERalpha GSE94023.ESR1.MCF-7_E2-10min-ERalpha 57 bp overlap
ChIP MCF-7_E2-1280-min-ERalpha GSE94023.ESR1.MCF-7_E2-1280-min-ERalpha 75 bp overlap
ChIP MCF-7_E2-40min-ERalpha GSE94023.ESR1.MCF-7_E2-40min-ERalpha 81 bp overlap
ChIP MCF-7_E2-5min-ERalpha GSE94023.ESR1.MCF-7_E2-5min-ERalpha 63 bp overlap
ChIP MCF-7_E2-80min-ERalpha GSE94023.ESR1.MCF-7_E2-80min-ERalpha 56 bp overlap
ChIP MCF-7_E2PG GSE68356.ESR1.MCF-7_E2PG 200 bp overlap
ChIP MCF-7_E2_3h GSE108883.ESR1.MCF-7_E2_3h 164 bp overlap
ChIP MCF-7_E2_45m GSE67295.ESR1.MCF-7_E2_45m 141 bp overlap
ChIP MCF-7_E2_45min GSE109820.ESR1.MCF-7_E2_45min 226 bp overlap
ChIP MCF-7_E2_90min GSE109820.ESR1.MCF-7_E2_90min 167 bp overlap
ChIP MCF-7_E2_talen GSE94493.ESR1.MCF-7_E2_talen 129 bp overlap
ChIP MCF-7_G6274 GSE117941.ESR1.MCF-7_G6274 274 bp overlap
ChIP MCF-7_HC11 GSE102882.ESR1.MCF-7_HC11 264 bp overlap
ChIP MCF-7_ICI GSE125594.ESR1.MCF-7_ICI 142 bp overlap
ChIP MCF-7_KO GSE136673.ESR1.MCF-7_KO 190 bp overlap
ChIP MCF-7_Millipore GSE128208.ESR1.MCF-7_Millipore 110 bp overlap
ChIP MCF-7_OBHS GSE133941.ESR1.MCF-7_OBHS 385 bp overlap
ChIP MCF-7_PROG GSE68355.ESR1.MCF-7_PROG 235 bp overlap
ChIP MCF-7_R5020 GSE68355.ESR1.MCF-7_R5020 245 bp overlap
ChIP MCF-7_RAD001 GSE103023.ESR1.MCF-7_RAD001 292 bp overlap
ChIP MCF-7_SHCTR_E2 GSE60270.ESR1.MCF-7_SHCTR_E2 51 bp overlap
ChIP MCF-7_SICTR_E2 GSE40129.ESR1.MCF-7_SICTR_E2 166 bp overlap
ChIP MCF-7_SIGATA_E2 GSE40129.ESR1.MCF-7_SIGATA_E2 160 bp overlap
ChIP MCF-7_Santacruz GSE128208.ESR1.MCF-7_Santacruz 107 bp overlap
ChIP MCF-7_TNFa_45m GSE67295.ESR1.MCF-7_TNFa_45m 56 bp overlap
ChIP MCF-7_TamR GSE128445.ESR1.MCF-7_TamR 184 bp overlap
ChIP MCF-7_Veh GSE95302.ESR1.MCF-7_Veh 232 bp overlap
ChIP MCF-7_Veh_sc GSE117569.ESR1.MCF-7_Veh_sc 106 bp overlap
ChIP MCF-7_Y537S_DMSO GSE148277.ESR1.MCF-7_Y537S_DMSO 297 bp overlap
ChIP MCF-7_estradiol-DHT_4h GSE99626.ESR1.MCF-7_estradiol-DHT_4h 292 bp overlap
ChIP MCF-7_estradiol-Dex_4h GSE99626.ESR1.MCF-7_estradiol-Dex_4h 142 bp overlap
ChIP MCF-7_estradiol-aldosterone_4h GSE99626.ESR1.MCF-7_estradiol-aldosterone_4h 212 bp overlap
ChIP MCF-7_estradiol-progesterone_4h GSE99626.ESR1.MCF-7_estradiol-progesterone_4h 212 bp overlap
ChIP MCF-7_estradiol_4h GSE99626.ESR1.MCF-7_estradiol_4h 372 bp overlap
ChIP MCF-7_estrogen GSE133941.ESR1.MCF-7_estrogen 357 bp overlap
ChIP MCF-7_jc5849 GSE126004.ESR1.MCF-7_jc5849 229 bp overlap
ChIP MCF-7_jc5850 GSE126004.ESR1.MCF-7_jc5850 365 bp overlap
ChIP MCF-7_jc5852 GSE126004.ESR1.MCF-7_jc5852 228 bp overlap
ChIP MCF-7_jc5853 GSE126004.ESR1.MCF-7_jc5853 177 bp overlap
ChIP MCF-7_jc5854 GSE126004.ESR1.MCF-7_jc5854 231 bp overlap
ChIP MCF-7_jc5855 GSE126004.ESR1.MCF-7_jc5855 213 bp overlap
ChIP MCF-7_jc5856 GSE126004.ESR1.MCF-7_jc5856 201 bp overlap
ChIP MCF-7_parental GSE123284.ESR1.MCF-7_parental 312 bp overlap
ChIP MCF-7_parental_4-hydroxytamoxifen GSE123284.ESR1.MCF-7_parental_4-hydroxytamoxifen 347 bp overlap
ChIP MCF-7_shCtrl GSE125594.ESR1.MCF-7_shCtrl 157 bp overlap
ChIP MCF-7_shKMT2C GSE100328.ESR1.MCF-7_shKMT2C 224 bp overlap
ChIP MCF-7_shKMT2C_R GSE100328.ESR1.MCF-7_shKMT2C_R 62 bp overlap
ChIP MCF-7_shTEAD4 GSE125594.ESR1.MCF-7_shTEAD4 214 bp overlap
ChIP MCF-7_shYAP1 GSE125594.ESR1.MCF-7_shYAP1 171 bp overlap
ChIP MCF-7_vehicle_4h GSE99626.ESR1.MCF-7_vehicle_4h 100 bp overlap
ChIP MDA-MB-134-VI_E2 GSE109103.ESR1.MDA-MB-134-VI_E2 183 bp overlap
ChIP MDA-MB-134-VI_FI GSE109103.ESR1.MDA-MB-134-VI_FI 166 bp overlap
ChIP SUM44PE_ESR1_wildtype GSE100074.ESR1.SUM44PE_ESR1_wildtype 102 bp overlap
ChIP T-47D ENCSR000BKN.ESR1.T-47D 83 bp overlap
ChIP T-47D ENCSR000BJS.ESR1.T-47D 69 bp overlap
ChIP T-47D_D538G_E2 GSE148277.ESR1.T-47D_D538G_E2 56 bp overlap
ChIP ZR751 ERP000783.ESR1.ZR751 57 bp overlap
ChIP ZR751 GSE72249.ESR1.ZR751 54 bp overlap
ChIP ZR751_E2 GSE72249.ESR1.ZR751_E2 123 bp overlap
ChIP breast-cancer GSE127859.ESR1.breast-cancer 160 bp overlap
ESR1_D538G 1 dataset
ChIP MCF-7_dox_E2 GSE94493.ESR1_D538G.MCF-7_dox_E2 131 bp overlap
ESR1_Y537N 1 dataset
ChIP MCF-7_dox GSE94493.ESR1_Y537N.MCF-7_dox 139 bp overlap
ESR1_Y537S 2 datasets
ChIP MCF-7_E2 GSE94493.ESR1_Y537S.MCF-7_E2 143 bp overlap
ChIP MCF-7_dox GSE94493.ESR1_Y537S.MCF-7_dox 190 bp overlap
ESR1_pS118 1 dataset
ChIP MCF-7_E2_sc GSE117569.ESR1_pS118.MCF-7_E2_sc 124 bp overlap
FOXA1 24 datasets
ChIP MCF-7 GSE81714.FOXA1.MCF-7 357 bp overlap
ChIP MCF-7 ERP001226.FOXA1.MCF-7 315 bp overlap
ChIP MCF-7 GSE124667.FOXA1.MCF-7 269 bp overlap
ChIP MCF-7 GSE80808.FOXA1.MCF-7 121 bp overlap
ChIP MCF-7_1117 GSE124667.FOXA1.MCF-7_1117 208 bp overlap
ChIP MCF-7_1118 GSE124667.FOXA1.MCF-7_1118 221 bp overlap
ChIP MCF-7_E2 GSE72249.FOXA1.MCF-7_E2 228 bp overlap
ChIP MCF-7_E2_TAM ERP000380.FOXA1.MCF-7_E2_TAM 305 bp overlap
ChIP MCF-7_ESR1 GSE124667.FOXA1.MCF-7_ESR1 58 bp overlap
ChIP MCF-7_ETOH GSE23852.FOXA1.MCF-7_ETOH 91 bp overlap
ChIP MCF-7_JC4690 GSE126004.FOXA1.MCF-7_JC4690 99 bp overlap
ChIP MCF-7_JC4691 GSE126004.FOXA1.MCF-7_JC4691 90 bp overlap
ChIP MCF-7_JC4692 GSE126004.FOXA1.MCF-7_JC4692 134 bp overlap
ChIP MCF-7_JC4693 GSE126004.FOXA1.MCF-7_JC4693 113 bp overlap
ChIP MCF-7_JC4694 GSE126004.FOXA1.MCF-7_JC4694 59 bp overlap
ChIP MCF-7_JC4697 GSE126004.FOXA1.MCF-7_JC4697 53 bp overlap
ChIP MCF-7_TamR GSE128445.FOXA1.MCF-7_TamR 113 bp overlap
ChIP MCF-7_estrogen_ab1 GSE112969.FOXA1.MCF-7_estrogen_ab1 108 bp overlap
ChIP MCF-7_estrogen_ab2 GSE112969.FOXA1.MCF-7_estrogen_ab2 160 bp overlap
ChIP MCF-7_vehicle_ab2 GSE112969.FOXA1.MCF-7_vehicle_ab2 253 bp overlap
ChIP ZR-75-1_vehicle_ab2 GSE112969.FOXA1.ZR-75-1_vehicle_ab2 74 bp overlap
ChIP ZR751 GSE72249.FOXA1.ZR751 197 bp overlap
ChIP ZR751_DEX GSE72249.FOXA1.ZR751_DEX 57 bp overlap
ChIP ZR751_E2 GSE72249.FOXA1.ZR751_E2 144 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 327 bp overlap
ChIP DE DE-FOXA2-2 333 bp overlap
FOXM1 1 dataset
ChIP MCF-7 ENCSR000BUJ.FOXM1.MCF-7 57 bp overlap
GATA3 7 datasets
ChIP MCF-7 ENCFF437NQS 131 bp overlap
ChIP MCF-7 GSE133072.GATA3.MCF-7 264 bp overlap
ChIP MCF-7 GSE122847.GATA3.MCF-7 209 bp overlap
ChIP MCF-7 ENCSR000EWV.GATA3.MCF-7 170 bp overlap
ChIP MCF-7_E2 GSE81510.GATA3.MCF-7_E2 199 bp overlap
ChIP MCF-7_E2 GSE40129.GATA3.MCF-7_E2 159 bp overlap
ChIP MCF-7_sgScr GSE133072.GATA3.MCF-7_sgScr 265 bp overlap
GATA4 4 datasets
ChIP BJ1-hTERT GSE92491.GATA4.BJ1-hTERT 53 bp overlap
ChIP DE DE-GATA4-1 290 bp overlap
ChIP DE DE-GATA4-2 306 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 293 bp overlap
GATA6 10 datasets
ChIP DE DE-GATA6-1 274 bp overlap
ChIP DE DE-GATA6-2 306 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 245 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 318 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 327 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 341 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 317 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 318 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 356 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 255 bp overlap
HDAC1 1 dataset
ChIP MCF-7_parental_4-hydroxytamoxifen GSE123284.HDAC1.MCF-7_parental_4-hydroxytamoxifen 321 bp overlap
MED1 1 dataset
ChIP MCF-7 GSE76893.MED1.MCF-7 186 bp overlap
NRIP1 1 dataset
ChIP MCF-7_E2 ERP005838.NRIP1.MCF-7_E2 55 bp overlap
RELA 1 dataset
ChIP MCF-7_Veh GSE67295.RELA.MCF-7_Veh 121 bp overlap
SMARCA4 4 datasets
ChIP MCF-7_ARID1A-KO_4-OHT GSE123284.SMARCA4.MCF-7_ARID1A-KO_4-OHT 248 bp overlap
ChIP MCF-7_ARID1A-KO_4-OHT_clone14 GSE123284.SMARCA4.MCF-7_ARID1A-KO_4-OHT_clone14 104 bp overlap
ChIP MCF-7_ARID1A-KO_clone14 GSE123284.SMARCA4.MCF-7_ARID1A-KO_clone14 180 bp overlap
ChIP MCF-7_parental GSE123284.SMARCA4.MCF-7_parental 189 bp overlap
SMARCB1 3 datasets
ChIP MCF-7_4-hydroxytamoxifen GSE123284.SMARCB1.MCF-7_4-hydroxytamoxifen 215 bp overlap
ChIP MCF-7_JQ1 GSE123284.SMARCB1.MCF-7_JQ1 66 bp overlap
ChIP MCF-7_estrogen GSE123284.SMARCB1.MCF-7_estrogen 101 bp overlap
STAG1 1 dataset
ChIP MCF-7_E2_SHCTCF ERP000209.STAG1.MCF-7_E2_SHCTCF 72 bp overlap
STAT3 4 datasets
ChIP MCF-7_jc5834 GSE126004.STAT3.MCF-7_jc5834 268 bp overlap
ChIP MCF-7_jc5836 GSE126004.STAT3.MCF-7_jc5836 105 bp overlap
ChIP MCF-7_jc5838 GSE126004.STAT3.MCF-7_jc5838 164 bp overlap
ChIP MCF-7_jc5844 GSE126004.STAT3.MCF-7_jc5844 75 bp overlap
TAL1 1 dataset
ChIP PRIMA2 GSE33850.TAL1.PRIMA2 154 bp overlap
TRPS1 1 dataset
ChIP MCF-7 GSE133072.TRPS1.MCF-7 329 bp overlap
ZNF217 1 dataset
ChIP MCF-7 ENCSR000EWU.ZNF217.MCF-7 231 bp overlap
Huangfu Lab · Publications · Resources · Contact