chrX : 69,429,282 – 69,430,087

805 bp 57 TFs 3 linked genes

This 805 bp open chromatin element is linked to NALF2, EDA, and PJA1 and is bound by 57 transcription factors.

Linked Genes

3 genes

Gene	Dist. to TSS	Distance	Link type
NALF2	74.7 kb	Distal	Multiome+HiCAR
EDA	186.5 kb	Distal	Multiome
PJA1	264.2 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

57 transcription factors

AR 1 dataset

ChIP LNCaP-abl GSE39459.AR.LNCaP-abl 117 bp overlap

BHLHE22 2 datasets

Motif DE_60h DE_60h-BHLHE22_MA1635.2 6 bp overlap

Motif DE_72h DE_72h-BHLHE22_MA1635.2 6 bp overlap

Bhlha15 2 datasets

Motif DE_60h DE_60h-Bhlha15_MA1472.3 8 bp overlap

Motif DE_72h DE_72h-Bhlha15_MA1472.3 8 bp overlap

CEBPD 2 datasets

Motif DE_48h DE_48h-CEBPD_MA0836.3 8 bp overlap

Motif DE_60h DE_60h-CEBPD_MA0836.3 8 bp overlap

Crx 2 datasets

Motif DE_48h DE_48h-Crx_MA0467.3 6 bp overlap

Motif DE_60h DE_60h-Crx_MA0467.3 6 bp overlap

EOMES 2 datasets

ChIP hESC GSE26097.EOMES.hESC 251 bp overlap

ChIP hESC GSE26097.EOMES.hESC 240 bp overlap

ERF::FOXI1 2 datasets

Motif DE_48h DE_48h-ERFFOXI1_MA1935.2 10 bp overlap

Motif DE_60h DE_60h-ERFFOXI1_MA1935.2 10 bp overlap

ESR1 1 dataset

ChIP MCF-7_E2 GSE14664.ESR1.MCF-7_E2 94 bp overlap

ETV2 2 datasets

Motif DE_48h DE_48h-ETV2_MA0762.2 9 bp overlap

Motif DE_60h DE_60h-ETV2_MA0762.2 9 bp overlap

ETV2::FOXI1 2 datasets

Motif DE_48h DE_48h-ETV2FOXI1_MA1942.2 11 bp overlap

Motif DE_60h DE_60h-ETV2FOXI1_MA1942.2 11 bp overlap

Erg 2 datasets

Motif DE_48h DE_48h-Erg_MA0474.4 10 bp overlap

Motif DE_60h DE_60h-Erg_MA0474.4 10 bp overlap

FLI1::FOXI1 2 datasets

Motif DE_48h DE_48h-FLI1FOXI1_MA1950.2 11 bp overlap

Motif DE_60h DE_60h-FLI1FOXI1_MA1950.2 11 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 669 bp overlap

ChIP DE DE-FOXA2-2 679 bp overlap

FOXO1::ELF1 2 datasets

Motif DE_48h DE_48h-FOXO1ELF1_MA1953.2 13 bp overlap

Motif DE_60h DE_60h-FOXO1ELF1_MA1953.2 13 bp overlap

FOXO1::FLI1 2 datasets

Motif DE_48h DE_48h-FOXO1FLI1_MA1956.2 13 bp overlap

Motif DE_60h DE_60h-FOXO1FLI1_MA1956.2 13 bp overlap

GABPA 2 datasets

Motif DE_48h DE_48h-GABPA_MA0062.4 10 bp overlap

Motif DE_60h DE_60h-GABPA_MA0062.4 10 bp overlap

GATA4 4 datasets

ChIP DE DE-GATA4-1 795 bp overlap

ChIP DE DE-GATA4-2 805 bp overlap

ChIP foregut GSE117136.GATA4.foregut 779 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 607 bp overlap

GATA6 5 datasets

ChIP DE DE-GATA6-1 805 bp overlap

ChIP DE DE-GATA6-2 787 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 805 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 763 bp overlap

ChIP foregut GSE117136.GATA6.foregut 652 bp overlap

GSC 2 datasets

Motif DE_48h DE_48h-GSC_MA0648.2 6 bp overlap

Motif DE_60h DE_60h-GSC_MA0648.2 6 bp overlap

GSC2 2 datasets

Motif DE_48h DE_48h-GSC2_MA0891.2 6 bp overlap

Motif DE_60h DE_60h-GSC2_MA0891.2 6 bp overlap

KLF16 1 dataset

Motif DE_60h DE_60h-KLF16_MA0741.1 11 bp overlap

KLF4 1 dataset

ChIP BJ_INDUCED GSE36570.KLF4.BJ_INDUCED 226 bp overlap

KLF9 1 dataset

Motif DE_60h DE_60h-KLF9_MA1107.3 11 bp overlap

MYF5 2 datasets

Motif DE_60h DE_60h-MYF5_MA1641.2 8 bp overlap

Motif DE_72h DE_72h-MYF5_MA1641.2 8 bp overlap

Mecom 1 dataset

Motif DE_60h DE_60h-Mecom_MA0029.2 11 bp overlap

NEUROD1 2 datasets

Motif DE_60h DE_60h-NEUROD1_MA1109.2 8 bp overlap

Motif DE_72h DE_72h-NEUROD1_MA1109.2 8 bp overlap

Neurod2 4 datasets

Motif DE_60h DE_60h-Neurod2_MA0668.3 8 bp overlap

Motif DE_60h DE_60h-Neurod2_MA1993.2 6 bp overlap

Motif DE_72h DE_72h-Neurod2_MA0668.3 8 bp overlap

Motif DE_72h DE_72h-Neurod2_MA1993.2 6 bp overlap

OTX1 2 datasets

Motif DE_48h DE_48h-OTX1_MA0711.2 6 bp overlap

Motif DE_60h DE_60h-OTX1_MA0711.2 6 bp overlap

Olig2 2 datasets

Motif DE_60h DE_60h-Olig2_MA1997.2 6 bp overlap

Motif DE_72h DE_72h-Olig2_MA1997.2 6 bp overlap

PGR 1 dataset

ChIP myometrium_NP1 GSE137550.PGR.myometrium_NP1 433 bp overlap

PITX1 2 datasets

Motif DE_48h DE_48h-PITX1_MA0682.3 6 bp overlap

Motif DE_60h DE_60h-PITX1_MA0682.3 6 bp overlap

PITX3 2 datasets

Motif DE_48h DE_48h-PITX3_MA0714.2 6 bp overlap

Motif DE_60h DE_60h-PITX3_MA0714.2 6 bp overlap

PRDM9 1 dataset

Motif DE_60h DE_60h-PRDM9_MA1723.2 20 bp overlap

Ptf1A 2 datasets

Motif DE_60h DE_60h-Ptf1A_MA1619.2 8 bp overlap

Motif DE_72h DE_72h-Ptf1A_MA1619.2 8 bp overlap

RHOXF1 2 datasets

Motif DE_48h DE_48h-RHOXF1_MA0719.2 6 bp overlap

Motif DE_60h DE_60h-RHOXF1_MA0719.2 6 bp overlap

SMAD2 2 datasets

ChIP endoderm GSE29422.SMAD2.endoderm 228 bp overlap

ChIP endoderm GSE29422.SMAD2.endoderm 325 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 805 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 805 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 805 bp overlap

SMAD3 2 datasets

ChIP endoderm GSE29422.SMAD3.endoderm 161 bp overlap

ChIP endoderm GSE29422.SMAD3.endoderm 255 bp overlap

SMAD4 2 datasets

ChIP endoderm GSE29422.SMAD4.endoderm 230 bp overlap

ChIP endoderm GSE29422.SMAD4.endoderm 283 bp overlap

SOX10 2 datasets

Motif DE_48h DE_48h-SOX10_MA0442.3 6 bp overlap

Motif DE_60h DE_60h-SOX10_MA0442.3 6 bp overlap

SOX11 1 dataset

ChIP GRANT-A519 GSE52146.SOX11.GRANT-A519 90 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 697 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 787 bp overlap

SP8 1 dataset

Motif DE_60h DE_60h-SP8_MA0747.2 11 bp overlap

SP9 1 dataset

Motif DE_60h DE_60h-SP9_MA1564.2 10 bp overlap

SS18-SSX 1 dataset

ChIP fibroblast_W164A GSE139053.SS18-SSX.fibroblast_W164A 250 bp overlap

STAT3 1 dataset

ChIP T-47D_JC5056 GSE126004.STAT3.T-47D_JC5056 254 bp overlap

Tcf12 2 datasets

Motif DE_60h DE_60h-Tcf12_MA0521.3 6 bp overlap

Motif DE_72h DE_72h-Tcf12_MA0521.3 6 bp overlap

Twist2 2 datasets

Motif DE_60h DE_60h-Twist2_MA0633.3 6 bp overlap

Motif DE_72h DE_72h-Twist2_MA0633.3 6 bp overlap

Wt1 1 dataset

Motif DE_60h DE_60h-Wt1_MA1627.2 10 bp overlap

ZBTB18 2 datasets

Motif DE_60h DE_60h-ZBTB18_MA0698.2 11 bp overlap

Motif DE_72h DE_72h-ZBTB18_MA0698.2 11 bp overlap

ZNF582 2 datasets

Motif DE_60h DE_60h-ZNF582_MA1983.2 19 bp overlap

Motif DE_72h DE_72h-ZNF582_MA1983.2 19 bp overlap

ZNF740 1 dataset

Motif DE_60h DE_60h-ZNF740_MA0753.3 10 bp overlap

ZNF85 1 dataset

Motif DE_60h DE_60h-ZNF85_MA1720.2 12 bp overlap

ZNF90 1 dataset

ChIP HEK293T GSE78099.ZNF90.HEK293T 254 bp overlap

Zic2 2 datasets

Motif DE_60h DE_60h-Zic2_MA1629.2 9 bp overlap

Motif DE_72h DE_72h-Zic2_MA1629.2 9 bp overlap