This module contains 28 genes including PNPLA3, STAT4, EDNRA, JUP, and ST3GAL5, with enrichment in lipid metabolism, cell adhesion, and endothelin signaling. Knockdown of MIXL1 and TIGD1 activates this module. Knockdown of DR1, MARS, and ZNF431 represses this module.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.