chr5:138,247,699–138,248,212

chr5 : 138,247,699 – 138,248,212

513 bp 13 TFs 10 linked genes

This 513 bp open chromatin element is linked to 10 target genes and is bound by 13 transcription factors.

Linked Genes

10 genes

Gene	Expression	Dist. to TSS	Distance	Link type
CDC23		34.6 kb	Distal	Multiome
KIF20A		68.8 kb	Distal	Multiome
BRD8		69.0 kb	Distal	Multiome
CDC25C		83.8 kb	Distal	Multiome
FAM53C		84.1 kb	Distal	Multiome
KDM3B		104.7 kb	Distal	Multiome
NME5		108.5 kb	Distal	Multiome
REEP2		191.1 kb	Distal	Multiome
FAM13B		214.9 kb	Distal	Multiome
ETF1		295.3 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

13 transcription factors

Cebpa 2 datasets

ChIP BLaER1 ENCFF031ISE 180 bp overlap

ChIP BLaER1 ENCFF364PUR 245 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 337 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 513 bp overlap

ChIP DE DE-FOXA2-2 513 bp overlap

GATA4 4 datasets

ChIP DE DE-GATA4-1 495 bp overlap

ChIP DE DE-GATA4-2 513 bp overlap

ChIP Hep-G2 GSE135714.GATA4.Hep-G2 339 bp overlap

ChIP foregut GSE117136.GATA4.foregut 432 bp overlap

GATA6 10 datasets

ChIP DE DE-GATA6-1 509 bp overlap

ChIP DE DE-GATA6-2 513 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 426 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 418 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 458 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 513 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 469 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 490 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 508 bp overlap

ChIP foregut GSE117136.GATA6.foregut 494 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 471 bp overlap

ChIP DE_D2 S54-DE-d2-JUN-exp2 275 bp overlap

POLR2A 1 dataset

ChIP neural cell ENCFF604SPB 145 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 190 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 488 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 315 bp overlap

SMAD2_3 3 datasets

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 270 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 513 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 495 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 349 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 511 bp overlap

ZNF22 1 dataset

ChIP HEK293 GSE76494.ZNF22.HEK293 136 bp overlap