chr4 : 130,288,676 – 130,289,703

1,027 bp 48 TFs 0 linked genes

This 1.0 kb open chromatin element has no linked target genes and is bound by 48 transcription factors.

Linked Genes

No linked genes

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

48 transcription factors

BHLHE22 1 dataset

Motif DE_60h DE_60h-BHLHE22_MA1635.2 6 bp overlap

CHD7 1 dataset

ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 265 bp overlap

ELF3 1 dataset

ChIP PDAC_SHCTR GSE64557.ELF3.PDAC_SHCTR 230 bp overlap

EOMES 2 datasets

ChIP hESC GSE26097.EOMES.hESC 195 bp overlap

ChIP hESC GSE26097.EOMES.hESC 252 bp overlap

ERG 1 dataset

ChIP aortic-endothelial-cell_D1 GSE139377.ERG.aortic-endothelial-cell_D1 169 bp overlap

Esrrg 1 dataset

Motif DE_60h DE_60h-Esrrg_MA0643.2 9 bp overlap

FLI1 4 datasets

ChIP A-673_1_KRAB_GFP GSE106914.FLI1.A-673_1_KRAB_GFP 291 bp overlap

ChIP A-673_2_KRAB_eSOX2_1 GSE106914.FLI1.A-673_2_KRAB_eSOX2_1 202 bp overlap

ChIP A-673_D11 GSE129155.FLI1.A-673_D11 76 bp overlap

ChIP A-673_D17 GSE129155.FLI1.A-673_D17 217 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 1027 bp overlap

ChIP DE DE-FOXA2-2 996 bp overlap

GATA4 5 datasets

ChIP DE DE-GATA4-1 1027 bp overlap

ChIP DE DE-GATA4-2 351 bp overlap

ChIP DE DE-GATA4-2 564 bp overlap

ChIP Hep-G2 GSE135714.GATA4.Hep-G2 206 bp overlap

ChIP foregut GSE117136.GATA4.foregut 259 bp overlap

GATA6 6 datasets

ChIP DE DE-GATA6-1 364 bp overlap

ChIP DE DE-GATA6-1 440 bp overlap

ChIP DE DE-GATA6-2 1027 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 331 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 310 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 507 bp overlap

Hmx2 1 dataset

Motif DE_60h DE_60h-Hmx2_MA0897.2 15 bp overlap

NANOG 2 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 257 bp overlap

ChIP hESC GSE18292.NANOG.hESC 102 bp overlap

NCOR2 1 dataset

ChIP LS180 GSE39277.NCOR2.LS180 101 bp overlap

NFYB 1 dataset

Motif DE_60h DE_60h-NFYB_MA0502.3 9 bp overlap

NKX2-4 1 dataset

Motif DE_60h DE_60h-NKX2-4_MA2003.2 8 bp overlap

NKX2-8 1 dataset

Motif DE_60h DE_60h-NKX2-8_MA0673.2 8 bp overlap

Neurod2 1 dataset

Motif DE_60h DE_60h-Neurod2_MA1993.2 6 bp overlap

Nkx2-1 1 dataset

Motif DE_60h DE_60h-Nkx2-1_MA1994.2 7 bp overlap

ONECUT1 1 dataset

ChIP pancreatic-progenitor_PP1 GSE104840.ONECUT1.pancreatic-progenitor_PP1 440 bp overlap

Olig2 1 dataset

Motif DE_60h DE_60h-Olig2_MA1997.2 6 bp overlap

PRDM1 1 dataset

ChIP fetal_testis GSE100639.PRDM1.fetal_testis 269 bp overlap

RARA 1 dataset

Motif DE_60h DE_60h-RARA_MA0730.1 17 bp overlap

RARA::RXRA 1 dataset

Motif DE_60h DE_60h-RARARXRA_MA0159.1 17 bp overlap

RARA::RXRG 1 dataset

Motif DE_60h DE_60h-RARARXRG_MA1149.2 17 bp overlap

RELA 3 datasets

ChIP aortic-endothelial-cell_IL1B_D14 GSE139377.RELA.aortic-endothelial-cell_IL1B_D14 177 bp overlap

ChIP aortic-endothelial-cell_IL1B_D16 GSE139377.RELA.aortic-endothelial-cell_IL1B_D16 170 bp overlap

ChIP aortic-endothelial-cell_IL1B_D4 GSE139377.RELA.aortic-endothelial-cell_IL1B_D4 175 bp overlap

Rarb 1 dataset

Motif DE_60h DE_60h-Rarb_MA0858.1 17 bp overlap

SIX2 1 dataset

ChIP HEK GSE73865.SIX2.HEK 160 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 187 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 1027 bp overlap

SMAD2_3 3 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 220 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 558 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 382 bp overlap

SMAD4 1 dataset

ChIP endoderm GSE29422.SMAD4.endoderm 178 bp overlap

SOX14 1 dataset

Motif DE_60h DE_60h-SOX14_MA1562.2 9 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 200 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 377 bp overlap

SOX18 1 dataset

Motif DE_60h DE_60h-SOX18_MA1563.2 8 bp overlap

SOX8 1 dataset

Motif DE_60h DE_60h-SOX8_MA0868.3 7 bp overlap

SOX9 1 dataset

Motif DE_60h DE_60h-SOX9_MA0077.2 8 bp overlap

Sox11 1 dataset

Motif DE_60h DE_60h-Sox11_MA0869.3 8 bp overlap

Sox17 1 dataset

Motif DE_60h DE_60h-Sox17_MA0078.3 10 bp overlap

Sox5 1 dataset

Motif DE_60h DE_60h-Sox5_MA0087.3 8 bp overlap

Sox6 1 dataset

Motif DE_60h DE_60h-Sox6_MA0515.1 10 bp overlap

Sox7 1 dataset

Motif DE_60h DE_60h-Sox7_MA2095.1 10 bp overlap

T 2 datasets

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 136 bp overlap

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 212 bp overlap

Tcf12 1 dataset

Motif DE_60h DE_60h-Tcf12_MA0521.3 6 bp overlap

Twist2 1 dataset

Motif DE_60h DE_60h-Twist2_MA0633.3 6 bp overlap

ZNF16 1 dataset

Motif DE_60h DE_60h-ZNF16_MA1654.2 21 bp overlap

ZNF768 1 dataset

Motif DE_60h DE_60h-ZNF768_MA1731.2 9 bp overlap

Zfp961 1 dataset

Motif DE_60h DE_60h-Zfp961_MA2126.1 8 bp overlap