chr5:176,172,154–176,172,641

chr5 : 176,172,154 – 176,172,641

487 bp 15 TFs 11 linked genes

This 487 bp open chromatin element is linked to 11 target genes and is bound by 15 transcription factors.

Linked Genes

11 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000287579		3.8 kb	Proximal	Proximity
ENSG00000290935		17.0 kb	Distal	Multiome
ENSG00000283235		26.7 kb	Distal	Multiome
SIMC1		65.8 kb	Distal	Multiome
KIAA1191		189.2 kb	Distal	Multiome
ARL10		192.9 kb	Distal	Multiome
THOC3		204.3 kb	Distal	Multiome
NOP16		216.1 kb	Distal	Multiome
HIGD2A		216.2 kb	Distal	Multiome
CLTB		244.0 kb	Distal	Multiome
FAF2		275.8 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

15 transcription factors

CBFA2T3 1 dataset

ChIP K562 ENCFF673OEZ 361 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF460KDD 136 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 423 bp overlap

ChIP DE DE-FOXA2-2 442 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 443 bp overlap

ChIP DE DE-GATA4-2 441 bp overlap

GATA6 9 datasets

ChIP DE DE-GATA6-1 410 bp overlap

ChIP DE DE-GATA6-2 487 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 487 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 474 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 443 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 409 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 443 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 428 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 308 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 435 bp overlap

NANOG 4 datasets

ChIP GM23338 ENCFF065NZG 311 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 316 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 405 bp overlap

ChIP hESC GSE18292.NANOG.hESC 204 bp overlap

POU5F1 3 datasets

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 429 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 388 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 259 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 388 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 430 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 445 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 449 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 487 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 487 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 432 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 346 bp overlap

SMARCC1 1 dataset

ChIP DE_D1 S15-DE-d1-BAF155-exp1 446 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 255 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 467 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 244 bp overlap

ChIP K562 ENCFF319QZT 317 bp overlap