chr5:153,970,477–153,971,077

chr5 : 153,970,477 – 153,971,077

600 bp 31 TFs 5 linked genes

This 600 bp open chromatin element is linked to 5 target genes and is bound by 31 transcription factors.

Linked Genes

5 genes

Gene	Expression	Dist. to TSS	Distance	Link type
FAM114A2		68.2 kb	Distal	Multiome+HiCAR
MFAP3		68.3 kb	Distal	Multiome+HiCAR
GALNT10		220.0 kb	Distal	Multiome+HiCAR
SAP30L-AS1		475.1 kb	Distal	Multiome+HiCAR
SAP30L		475.3 kb	Distal	Multiome+HiCAR

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

31 transcription factors

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 522 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 265 bp overlap

FOXA1 2 datasets

ChIP 22Rv1_CST_Crispr-70 GSE123618.FOXA1.22Rv1_CST_Crispr-70 66 bp overlap

ChIP LNCaP_SHFOXA1_R1881 GSE37345.FOXA1.LNCaP_SHFOXA1_R1881 108 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 439 bp overlap

ChIP DE DE-FOXA2-2 449 bp overlap

FOXC2 1 dataset

Motif DE_48h DE_48h-FOXC2_MA0846.2 11 bp overlap

FOXO1::ELK3 1 dataset

Motif DE_48h DE_48h-FOXO1ELK3_MA1955.2 13 bp overlap

FOXO6 1 dataset

Motif DE_48h DE_48h-FOXO6_MA0849.1 7 bp overlap

Foxj2 1 dataset

Motif DE_48h DE_48h-Foxj2_MA0614.1 8 bp overlap

Foxj3 1 dataset

Motif DE_48h DE_48h-Foxj3_MA0851.2 9 bp overlap

GATA2 1 dataset

ChIP hiPSC_SLC6ebs GSE107639.GATA2.hiPSC_SLC6ebs 191 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 355 bp overlap

ChIP DE DE-GATA4-2 490 bp overlap

GATA6 6 datasets

ChIP DE DE-GATA6-1 335 bp overlap

ChIP DE DE-GATA6-2 600 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 489 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 312 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 357 bp overlap

ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 325 bp overlap

ChIP K-562_EPZ GSE129380.IRF1.K-562_EPZ 178 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 302 bp overlap

MED26 1 dataset

ChIP HEK293T GSE121024.MED26.HEK293T 367 bp overlap

MEIS1 1 dataset

Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap

RREB1 1 dataset

Motif DE_48h DE_48h-RREB1_MA0073.2 19 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 296 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 600 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 376 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 581 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 549 bp overlap

SMAD3 1 dataset

ChIP endoderm GSE29422.SMAD3.endoderm 228 bp overlap

SMAD4 1 dataset

ChIP endoderm GSE29422.SMAD4.endoderm 303 bp overlap

SNAI2 1 dataset

ChIP RD GSE137168.SNAI2.RD 219 bp overlap

SOX10 1 dataset

Motif DE_48h DE_48h-SOX10_MA0442.3 6 bp overlap

SOX11 1 dataset

ChIP GRANT-A519 GSE52146.SOX11.GRANT-A519 90 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 209 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 302 bp overlap

Motif DE_48h DE_48h-SOX4_MA0867.3 8 bp overlap

Sox11 1 dataset

Motif DE_48h DE_48h-Sox11_MA0869.3 8 bp overlap

Motif DE_48h DE_48h-ZIM3_MA1709.2 11 bp overlap

ZNF680 1 dataset

Motif DE_48h DE_48h-ZNF680_MA1729.2 11 bp overlap