chr19:6,656,104–6,656,671

chr19 : 6,656,104 – 6,656,671

567 bp 10 TFs 13 linked genes

This 567 bp open chromatin element is linked to 13 target genes and is bound by 10 transcription factors.

Linked Genes

13 genes

Gene	Expression	Dist. to TSS	Distance	Link type
TNFSF14		13.7 kb	Distal	Multiome
CD70		65.3 kb	Distal	Multiome
C3		74.1 kb	Distal	Multiome
GPR108		81.1 kb	Distal	Multiome
TRIP10		83.3 kb	Distal	Multiome
SH2D3A		111.0 kb	Distal	Multiome
ENSG00000275234		187.0 kb	Distal	Multiome
CRB3		192.2 kb	Distal	Multiome
SLC25A23		196.7 kb	Distal	Multiome
KHSRP		231.6 kb	Distal	Multiome
GTF2F1		263.3 kb	Distal	Multiome
ALKBH7		283.6 kb	Distal	Multiome
CLPP		294.9 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

10 transcription factors

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 341 bp overlap

ChIP DE DE-FOXA2-2 383 bp overlap

GATA4 4 datasets

ChIP DE DE-GATA4-1 420 bp overlap

ChIP DE DE-GATA4-2 546 bp overlap

ChIP foregut GSE117136.GATA4.foregut 345 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 527 bp overlap

GATA6 14 datasets

ChIP Caco-2_PROLIF GSE23436.GATA6.Caco-2_PROLIF 102 bp overlap

ChIP DE DE-GATA6-1 396 bp overlap

ChIP DE DE-GATA6-2 550 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 514 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 567 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 567 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 548 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 552 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 393 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 322 bp overlap

ChIP foregut GSE117136.GATA6.foregut 356 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 353 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 278 bp overlap

ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 323 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 329 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 313 bp overlap

NR4A1 1 dataset

ChIP K562 ENCFF998LHF 304 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 567 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 567 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 556 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 567 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 567 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 567 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 567 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 567 bp overlap

SMARCC1 1 dataset

ChIP DE_D1 S15-DE-d1-BAF155-exp1 343 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 396 bp overlap

ZNF592 1 dataset

ChIP K562 ENCFF547OSS 365 bp overlap