This module contains 10 genes including PRKCZ, TNK2, SH3KBP1, PPP3CC, and ERGIC1, with enriched terms related to protein kinase activity and endocytic pathways. Knockdown of SMAD5, SIRT6, SOX11, GRHL2, and SOX4 activates this module. Knockdown of SNAI1 represses this module.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.