Module DE-3.32 contains 12 genes including PTPRJ, ATG10, and HECW2, with enrichment in endocytosis and autophagy pathways. Knockdown of ARID1A, MIXL1, and TCEB3 activates this module. Knockdown of SMAD5, DR1, and VEZF1 represses this module.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.