This 17-gene module includes SRSF1, EIF4G1, NONO, LIG3, and MATR3, with enrichment in RNA splicing, mRNA processing, and transesterification reactions. Knockdown of E2F6 and FOXH1 represses this module, suggesting these factors support its expression.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.