This 27-gene module includes RAB1A, GFPT1, SEL1L, UGDH, and HYOU1, with enrichment for endoplasmic reticulum to Golgi vesicle-mediated transport, Golgi vesicle transport, transport vesicles, and response to endoplasmic reticulum stress. Knockdown of SNAI1, SOX11, DR1, HNF1B, and LIN28A activates this module. Knockdown of ARID1A, SMARCC1, and CNBP represses this module.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.