chr8 : 138,961,276 – 138,962,334
1,058 bp 33 TFs 1 linked gene
This 1.1 kb open chromatin element is linked to COL22A1 and is bound by 33 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
COL22A1 47.8 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr8:138,956,276 – 138,967,334
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
33 transcription factors
Source
Cell type
AR 1 dataset
ChIP MCF-7 ERP001226.AR.MCF-7 126 bp overlap
ARID1A 1 dataset
ChIP MCF-7_4-hydroxytamoxifen GSE123284.ARID1A.MCF-7_4-hydroxytamoxifen 366 bp overlap
BRD3 2 datasets
ChIP H-1_DE GSE126661.BRD3.H-1_DE 186 bp overlap
ChIP H-1_DE GSE126661.BRD3.H-1_DE 117 bp overlap
CEBPA 1 dataset
ChIP Kasumi-1_CEBPA-ER_E2 GSE102697.CEBPA.Kasumi-1_CEBPA-ER_E2 129 bp overlap
CTCF 1 dataset
Motif DE_48h DE_48h-CTCF_MA1930.2 33 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF335XTP 100 bp overlap
EP300 1 dataset
ChIP MCF-7 GSE128445.EP300.MCF-7 348 bp overlap
ESR1 62 datasets
ChIP MCF-7 ENCFF004AKH 361 bp overlap
ChIP MCF-7 GSE148277.ESR1.MCF-7 504 bp overlap
ChIP MCF-7 GSE45822.ESR1.MCF-7 350 bp overlap
ChIP MCF-7 GSE117492.ESR1.MCF-7 333 bp overlap
ChIP MCF-7 GSE128445.ESR1.MCF-7 337 bp overlap
ChIP MCF-7 GSE103023.ESR1.MCF-7 234 bp overlap
ChIP MCF-7 GSE68355.ESR1.MCF-7 261 bp overlap
ChIP MCF-7 GSE76893.ESR1.MCF-7 219 bp overlap
ChIP MCF-7 GSE48930.ESR1.MCF-7 197 bp overlap
ChIP MCF-7 GSE136302.ESR1.MCF-7 144 bp overlap
ChIP MCF-7 GSE41561.ESR1.MCF-7 126 bp overlap
ChIP MCF-7-Luc-Y537S_E2 GSE78284.ESR1.MCF-7-Luc-Y537S_E2 167 bp overlap
ChIP MCF-7_ARID1A-KO_4-OHT_clone14 GSE123284.ESR1.MCF-7_ARID1A-KO_4-OHT_clone14 159 bp overlap
ChIP MCF-7_D538G GSE148277.ESR1.MCF-7_D538G 367 bp overlap
ChIP MCF-7_D538G_DMSO GSE148277.ESR1.MCF-7_D538G_DMSO 325 bp overlap
ChIP MCF-7_DMSO GSE125594.ESR1.MCF-7_DMSO 447 bp overlap
ChIP MCF-7_E2 GSE60270.ESR1.MCF-7_E2 363 bp overlap
ChIP MCF-7_E2 GSE59530.ESR1.MCF-7_E2 240 bp overlap
ChIP MCF-7_E2 GSE71276.ESR1.MCF-7_E2 266 bp overlap
ChIP MCF-7_E2 GSE81510.ESR1.MCF-7_E2 373 bp overlap
ChIP MCF-7_E2 GSE108883.ESR1.MCF-7_E2 305 bp overlap
ChIP MCF-7_E2 GSE73956.ESR1.MCF-7_E2 186 bp overlap
ChIP MCF-7_E2 GSE86538.ESR1.MCF-7_E2 255 bp overlap
ChIP MCF-7_E2 ERP000209.ESR1.MCF-7_E2 216 bp overlap
ChIP MCF-7_E2 GSE14664.ESR1.MCF-7_E2 205 bp overlap
ChIP MCF-7_E2 ERP000380.ESR1.MCF-7_E2 174 bp overlap
ChIP MCF-7_E2-10min-ERalpha GSE94023.ESR1.MCF-7_E2-10min-ERalpha 230 bp overlap
ChIP MCF-7_E2-160min-ERalpha GSE94023.ESR1.MCF-7_E2-160min-ERalpha 153 bp overlap
ChIP MCF-7_E2-20min-ERalpha GSE94023.ESR1.MCF-7_E2-20min-ERalpha 263 bp overlap
ChIP MCF-7_E2-40min-ERalpha GSE94023.ESR1.MCF-7_E2-40min-ERalpha 268 bp overlap
ChIP MCF-7_E2-5min-ERalpha GSE94023.ESR1.MCF-7_E2-5min-ERalpha 267 bp overlap
ChIP MCF-7_E2-80min-ERalpha GSE94023.ESR1.MCF-7_E2-80min-ERalpha 259 bp overlap
ChIP MCF-7_E2_30min GSE108883.ESR1.MCF-7_E2_30min 181 bp overlap
ChIP MCF-7_E2_45m GSE67295.ESR1.MCF-7_E2_45m 411 bp overlap
ChIP MCF-7_E2_45min GSE109820.ESR1.MCF-7_E2_45min 228 bp overlap
ChIP MCF-7_E2_90min GSE109820.ESR1.MCF-7_E2_90min 301 bp overlap
ChIP MCF-7_E2_TNF GSE59530.ESR1.MCF-7_E2_TNF 161 bp overlap
ChIP MCF-7_LTED_E2 GSE86538.ESR1.MCF-7_LTED_E2 235 bp overlap
ChIP MCF-7_LY2_ETOH GSE54592.ESR1.MCF-7_LY2_ETOH 205 bp overlap
ChIP MCF-7_PROG GSE68355.ESR1.MCF-7_PROG 259 bp overlap
ChIP MCF-7_R5020 GSE68355.ESR1.MCF-7_R5020 206 bp overlap
ChIP MCF-7_SHCRT_E2 ERP000380.ESR1.MCF-7_SHCRT_E2 224 bp overlap
ChIP MCF-7_SHCTR_E2 GSE60270.ESR1.MCF-7_SHCTR_E2 239 bp overlap
ChIP MCF-7_SHCTR_E2_TNF GSE59530.ESR1.MCF-7_SHCTR_E2_TNF 185 bp overlap
ChIP MCF-7_SHFOXA1_E2_TNF GSE59530.ESR1.MCF-7_SHFOXA1_E2_TNF 182 bp overlap
ChIP MCF-7_SICTR_E2 GSE40129.ESR1.MCF-7_SICTR_E2 174 bp overlap
ChIP MCF-7_TNFa_45m GSE67295.ESR1.MCF-7_TNFa_45m 281 bp overlap
ChIP MCF-7_Veh_sc GSE117569.ESR1.MCF-7_Veh_sc 343 bp overlap
ChIP MCF-7_estradiol-Dex_4h GSE99626.ESR1.MCF-7_estradiol-Dex_4h 239 bp overlap
ChIP MCF-7_estradiol_4h GSE99626.ESR1.MCF-7_estradiol_4h 204 bp overlap
ChIP MCF-7_jc5849 GSE126004.ESR1.MCF-7_jc5849 205 bp overlap
ChIP MCF-7_jc5850 GSE126004.ESR1.MCF-7_jc5850 218 bp overlap
ChIP MCF-7_parental GSE123284.ESR1.MCF-7_parental 155 bp overlap
ChIP MCF-7_parental_4-hydroxytamoxifen GSE123284.ESR1.MCF-7_parental_4-hydroxytamoxifen 254 bp overlap
ChIP MCF-7_shCtrl GSE125594.ESR1.MCF-7_shCtrl 358 bp overlap
ChIP MCF-7_shTEAD4 GSE125594.ESR1.MCF-7_shTEAD4 360 bp overlap
ChIP MCF-7_shYAP1 GSE125594.ESR1.MCF-7_shYAP1 264 bp overlap
ChIP U2OS_100nM-E2 GSE151039.ESR1.U2OS_100nM-E2 431 bp overlap
ChIP U2OS_10nM-E2 GSE151039.ESR1.U2OS_10nM-E2 427 bp overlap
ChIP U2OS_10nM-E2-B GSE151039.ESR1.U2OS_10nM-E2-B 423 bp overlap
ChIP U2OS_E2 GSE26110.ESR1.U2OS_E2 115 bp overlap
ChIP U2OS_E2 GSE26110.ESR1.U2OS_E2 264 bp overlap
ESR1_D538G 3 datasets
ChIP MCF-7_E2 GSE94493.ESR1_D538G.MCF-7_E2 170 bp overlap
ChIP MCF-7_dox GSE94493.ESR1_D538G.MCF-7_dox 201 bp overlap
ChIP MCF-7_dox_E2 GSE94493.ESR1_D538G.MCF-7_dox_E2 244 bp overlap
ESR1_Y537N 2 datasets
ChIP MCF-7_dox GSE94493.ESR1_Y537N.MCF-7_dox 354 bp overlap
ChIP MCF-7_dox_E2 GSE94493.ESR1_Y537N.MCF-7_dox_E2 436 bp overlap
ESR1_Y537S 2 datasets
ChIP MCF-7_E2 GSE94493.ESR1_Y537S.MCF-7_E2 376 bp overlap
ChIP MCF-7_dox GSE94493.ESR1_Y537S.MCF-7_dox 363 bp overlap
ESR1_pS118 1 dataset
ChIP MCF-7_E2_sc GSE117569.ESR1_pS118.MCF-7_E2_sc 428 bp overlap
FIGLA 1 dataset
Motif DE_48h DE_48h-FIGLA_MA0820.2 6 bp overlap
FOXA1 1 dataset
ChIP MCF-7_4OH-Tam GSE75201.FOXA1.MCF-7_4OH-Tam 222 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 882 bp overlap
ChIP DE DE-FOXA2-2 821 bp overlap
GATA4 2 datasets
ChIP DE DE-GATA4-1 891 bp overlap
ChIP DE DE-GATA4-2 963 bp overlap
GATA6 9 datasets
ChIP DE DE-GATA6-1 906 bp overlap
ChIP DE DE-GATA6-2 900 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 983 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 948 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 808 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 922 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 1058 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 1008 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 484 bp overlap
JUN 5 datasets
ChIP DE_D1 S08-DE-d1-JUN-exp1 854 bp overlap
ChIP DE_D1 S40-DE-d1-JUN-exp2 917 bp overlap
ChIP DE_D2 S02-DE-d2-JUN-exp1 871 bp overlap
ChIP DE_D2 S54-DE-d2-JUN-exp2 275 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 505 bp overlap
NANOG 1 dataset
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 190 bp overlap
NHLH2 1 dataset
Motif DE_48h DE_48h-NHLH2_MA1529.2 16 bp overlap
NRIP1 1 dataset
ChIP MCF-7_E2 ERP005838.NRIP1.MCF-7_E2 132 bp overlap
POU2F3 1 dataset
Motif DE_48h DE_48h-POU2F3_MA0627.3 9 bp overlap
POU3F1 1 dataset
Motif DE_48h DE_48h-POU3F1_MA0786.2 10 bp overlap
POU5F1 2 datasets
ChIP DE_D1 DED1-OCT4_Batch_II 410 bp overlap
ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 422 bp overlap
POU5F1_M 1 dataset
ChIP DE_D1 DED1-OCT4-M_Batch_II 352 bp overlap
RELA 1 dataset
ChIP MCF-7_Veh GSE67295.RELA.MCF-7_Veh 355 bp overlap
SMAD2 2 datasets
ChIP hESC_YAP-_activinA_15h GSE99202.SMAD2.hESC_YAP-_activinA_15h 790 bp overlap
ChIP hESC_activinA_15h GSE99202.SMAD2.hESC_activinA_15h 654 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 1058 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 986 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 943 bp overlap
SMAD2_3 6 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 940 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 888 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 936 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 1058 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 875 bp overlap
ChIP ESC S33-ESC-d0-SMAD2_3-exp2 458 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 705 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 900 bp overlap
SREBF1 1 dataset
Motif DE_48h DE_48h-SREBF1_MA0829.3 10 bp overlap
ZEB1 1 dataset
Motif DE_48h DE_48h-ZEB1_MA0103.4 6 bp overlap
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