This 12-gene module includes MBOAT7, MLST8, CIB2, EPN1, and EMC10, with enrichment in membrane trafficking, endosomal processes, and protein-protein interactions. Knockdown of ZC3H3, ILF3, DR1, HNF1B, and SOX4 activates this module. Knockdown of ARID1A, CSNK2A1, SMARCC1, and CNBP represses this module.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.