This module contains 10 genes including HMGA2, ITGB5, MYOCD, TNFRSF21, and COLEC12, with enrichment in smooth muscle contraction, extracellular matrix organization, and cell adhesion. Knockdown of SOX17 activates this module, while knockdown of EOMESODERMIN, GSC, and FOXA2 repress it.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.