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DE-4.25

Submodule 12 genes

Anchoring junction assembly and cytoskeletal regulation

This module contains 12 genes including SRF, PRKAG2, DAPK3, FHOD1, and FBLIM1, with enrichment for anchoring junction components. No transcription factor knockdown data are available for this module. No repressing transcription factors are reported.

Key terms: regulation of cytoskeleton organization cell adhesion smooth muscle contraction regulation of smooth muscle contraction Notable genes: SRF PRKAG2 DAPK3 FHOD1 FBLIM1 LIMA1 RSU1 RBM24

TF Regulatory Network

Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).

Evidence: Direction: Max binding-only shown:
Perturbation + Binding ↑ ↓
Perturbation only ↑ ↓
Binding only
TF Dir NES #gRNA padj Bind OR

Enriched Terms

GO terms and pathway annotations enriched in this gene set (g:Profiler).

Module Genes (12)

All genes assigned to this co-expression submodule.

Gene Type Publications

Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.

Gene Co-expression Network

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Low
High z
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