DE-4

DE-4.20

Submodule 15 genes

Vesicular transport and endosomal sorting machinery

This module contains 15 genes including RALBP1, HGS, TNIP2, MKNK2, and CHMP1A, with top enriched terms related to vesicular transport, endosomal sorting, and membrane trafficking. No transcription factor knockdown data are available for this module. The module's role in the ESC-to-DE transition remains to be further characterized through additional functional studies.


TF Regulatory Network

Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).

Evidence: Direction: Max binding-only shown:
Perturbation + Binding
Perturbation only
Binding only
TF Dir NES #gRNA padj Bind OR

Enriched Terms

GO terms and pathway annotations enriched in this gene set (g:Profiler).


Module Genes (15)

All genes assigned to this co-expression submodule.

Gene Type Publications

Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.

Gene Co-expression Network

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Low
High z