This 18-gene module includes STAT5B, AXIN2, MYO5B, SGPL1, and WNK3, with enriched terms related to Wnt signaling and ion transport. Knockdown of MIXL1, SNAI1, and FOXH1 activates this module. Knockdown of HNF1B, ZNF431, and SMAD5 represses this module.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.