This module contains 19 genes, including CDK6, CLIP1, EEA1, and EPS15, with top enriched terms related to endocytic trafficking and cell cycle control. Knockdown of SOX17, FOXA2, and GATA6 activates this module. Knockdown of NANOG, OCT4, and KLF4 represses this module.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.