This 12-gene module includes PLXNB1, SEC16A, LMAN2L, and DLGAP4, with top enriched terms related to axon guidance, vesicular transport, and protein trafficking. Knockdown of FOXH1 and SETDB1 activates this module. Knockdown of VEZF1 represses this module.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.