chr1:25,968,758–25,969,159

chr1 : 25,968,758 – 25,969,159

401 bp 17 TFs 10 linked genes

This 401 bp open chromatin element is linked to 10 target genes and is bound by 17 transcription factors.

Linked Genes

10 genes

Gene	Expression	Dist. to TSS	Distance	Link type
PAFAH2		29.2 kb	Distal	Multiome
STMN1		62.5 kb	Distal	Multiome
PAQR7		93.2 kb	Distal	Multiome
AUNIP		109.5 kb	Distal	Multiome
PDIK1L		142.9 kb	Distal	Multiome
MTFR1L		148.9 kb	Distal	Multiome
SELENON		168.7 kb	Distal	Multiome
ZNF593		201.0 kb	Distal	Multiome
CNKSR1		208.6 kb	Distal	Multiome
CEP85		265.3 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

17 transcription factors

Cebpa 1 dataset

ChIP BLaER1 ENCFF364PUR 107 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 309 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 370 bp overlap

ChIP DE DE-FOXA2-2 331 bp overlap

GATA4 3 datasets

ChIP DE DE-GATA4-1 401 bp overlap

ChIP DE DE-GATA4-2 401 bp overlap

ChIP foregut GSE117136.GATA4.foregut 353 bp overlap

GATA6 9 datasets

ChIP DE DE-GATA6-1 401 bp overlap

ChIP DE DE-GATA6-2 401 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 342 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 342 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 401 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 401 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 401 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 401 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 401 bp overlap

HDAC3 1 dataset

ChIP RH4_DMSO-6H GSE116344.HDAC3.RH4_DMSO-6H 72 bp overlap

ChIP K-562 ENCSR563YDA.HDGF.K-562 401 bp overlap

ChIP NCI-H929 GSE56857.IRF4.NCI-H929 85 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 243 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 401 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 322 bp overlap

SMAD2_3 3 datasets

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 270 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 401 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 401 bp overlap

SMAD4 1 dataset

ChIP endoderm GSE29422.SMAD4.endoderm 217 bp overlap

SMARCA4 1 dataset

ChIP CTV-1_FLAG GSE128835.SMARCA4.CTV-1_FLAG 149 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 270 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 401 bp overlap

ZNF300 1 dataset

ChIP HEK293T GSE78099.ZNF300.HEK293T 86 bp overlap

ZNF770 3 datasets

ChIP HEK293 ENCFF468FCG 250 bp overlap

ChIP HEK293 ENCSR242BGR.ZNF770.HEK293 218 bp overlap

ChIP HEK293 GSE76494.ZNF770.HEK293 148 bp overlap