Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

32 transcription factors

BHLHE22 1 dataset

Motif DE_60h DE_60h-BHLHE22_MA1635.2 6 bp overlap

BRD4 3 datasets

ChIP Kelly_resistant GSE103030.BRD4.Kelly_resistant 333 bp overlap

ChIP Kelly_resistant_JQ1 GSE103030.BRD4.Kelly_resistant_JQ1 241 bp overlap

ChIP Kelly_sensitive GSE103030.BRD4.Kelly_sensitive 174 bp overlap

CTCF 1 dataset

ChIP GM12869 ENCSR000DRJ.CTCF.GM12869 98 bp overlap

DUX4 3 datasets

Motif DE_60h DE_60h-DUX4_MA0468.1 11 bp overlap

ChIP HEK293 GSE75791.DUX4.HEK293 352 bp overlap

ChIP WA01 GSE94322.DUX4.WA01 326 bp overlap

DUXA 1 dataset

Motif DE_60h DE_60h-DUXA_MA0884.2 13 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 172 bp overlap

ESR1 1 dataset

ChIP MCF-7_G6274 GSE117941.ESR1.MCF-7_G6274 182 bp overlap

FIGLA 1 dataset

Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 386 bp overlap

ChIP DE DE-FOXA2-2 353 bp overlap

GABPA 1 dataset

ChIP VCaP GSE49091.GABPA.VCaP 134 bp overlap

GATA4 3 datasets

ChIP DE DE-GATA4-1 440 bp overlap

ChIP DE DE-GATA4-2 466 bp overlap

ChIP foregut GSE117136.GATA4.foregut 272 bp overlap

GATA6 10 datasets

ChIP DE DE-GATA6-1 407 bp overlap

ChIP DE DE-GATA6-2 456 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 274 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 338 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 330 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 351 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 370 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 324 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 334 bp overlap

ChIP foregut GSE117136.GATA6.foregut 282 bp overlap

HDAC3 1 dataset

ChIP RH4_DMSO-6H GSE116344.HDAC3.RH4_DMSO-6H 231 bp overlap

HIF1A 1 dataset

ChIP U2OS_trough_DMOG GSE85096.HIF1A.U2OS_trough_DMOG 322 bp overlap

LHX6 1 dataset

Motif DE_60h DE_60h-LHX6_MA0658.2 8 bp overlap

NHLH1 1 dataset

Motif DE_60h DE_60h-NHLH1_MA0048.3 9 bp overlap

Neurod2 1 dataset

Motif DE_60h DE_60h-Neurod2_MA1993.2 6 bp overlap

Olig2 1 dataset

Motif DE_60h DE_60h-Olig2_MA1997.2 6 bp overlap

PHOX2A 1 dataset

Motif DE_60h DE_60h-PHOX2A_MA0713.1 11 bp overlap

PPARG 1 dataset

ChIP HUVEC-C_DMSO_HYPO GSE50144.PPARG.HUVEC-C_DMSO_HYPO 155 bp overlap

SIX2 1 dataset

ChIP HEK GSE73865.SIX2.HEK 63 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 267 bp overlap

SMC1A-B 1 dataset

ChIP Kelly_shLUC-res GSE115248.SMC1A-B.Kelly_shLUC-res 232 bp overlap

SOX10 1 dataset

Motif DE_60h DE_60h-SOX10_MA0442.3 6 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 220 bp overlap

Spz1 1 dataset

Motif DE_60h DE_60h-Spz1_MA0111.1 11 bp overlap

TCF7L2 1 dataset

Motif DE_60h DE_60h-TCF7L2_MA0523.2 9 bp overlap

Tcf12 1 dataset

Motif DE_60h DE_60h-Tcf12_MA0521.3 6 bp overlap

Twist2 1 dataset

Motif DE_60h DE_60h-Twist2_MA0633.3 6 bp overlap

ZEB1 1 dataset

Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap

ZNF574 2 datasets

Motif DE_60h DE_60h-ZNF574_MA1982.2 14 bp overlap

ChIP HEK293 GSE76494.ZNF574.HEK293 285 bp overlap

Zfx 1 dataset

Motif DE_60h DE_60h-Zfx_MA0146.3 10 bp overlap

Genome Browser