This 12-gene module includes E2F1, CASP8AP2, CCNE2, CDC45, and MCM6, and is enriched for regulation of cell cycle process and cell cycle phase transition. No transcription factor knockdown data are available for this module, limiting interpretation of its regulatory control during ESC-to-DE differentiation.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.