This 23-gene module includes BCL2L1, EFNB2, WWC1, ADAMTS1, and PNPT1, with enriched terms related to apoptosis regulation and extracellular matrix remodeling. Knockdown of PSMA1 and MYNN represses this module, suggesting these factors support its expression during endoderm differentiation.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.