This module contains 12 genes including HSPA4, MED1, MFN1, NSUN2, and PRPF8, with enrichment in heat shock response, protein synthesis, and molecular chaperone activity. Knockdown of SOX17, NANOG, and OCT4 activates this module. Knockdown of FOXA2, GATA6, and EOMESODERMIN represses this module.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.