This 14-gene module includes highly studied genes GOLPH3, TEAD4, MAML1, PRPF4B, and LUC7L3, with enriched terms related to Golgi apparatus organization and transcriptional coactivator activity. Knockdown of ZIC3 represses this module, suggesting ZIC3 normally supports its expression during endoderm differentiation.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.