DE-4

DE-4.9

Submodule 22 genes

Axonal and synaptic development pathways

This 22-gene module includes ERBB4, NTN1, NRP2, CNTNAP2, and PARD3, with strong enrichment for axon and synaptic membrane components, alongside terms for neuron projection morphogenesis and central nervous system development. No transcription factor knockdown data are available for this module.


TF Regulatory Network

Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).

Evidence: Direction: Max binding-only shown:
Perturbation + Binding
Perturbation only
Binding only
TF Dir NES #gRNA padj Bind OR

Enriched Terms

GO terms and pathway annotations enriched in this gene set (g:Profiler).


Module Genes (22)

All genes assigned to this co-expression submodule.

Gene Type Publications

Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.

Gene Co-expression Network

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Low
High z