This 23-gene module includes GAS5, CDKN1C, MAP1LC3A, BBC3, and TSPO, with enrichment for mitochondrial and organelle outer membrane components. Knockdown of FOXH1 and GATA4 represses this module, suggesting these factors positively regulate its expression during endoderm differentiation.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.