DE-4

DE-4.22

Submodule 13 genes

Lipid transport and chromatin remodeling factors

This module contains 13 genes including ABCA1, OGA, AMBRA1, SPRED2, and CHD2, with enrichment in lipid transport and chromatin modification processes. Knockdown of FOXH1 and SOX11 activates this module. Knockdown of ARID1A represses this module.


TF Regulatory Network

Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).

Evidence: Direction: Max binding-only shown:
Perturbation + Binding
Perturbation only
Binding only
TF Dir NES #gRNA padj Bind OR

Enriched Terms

GO terms and pathway annotations enriched in this gene set (g:Profiler).


Module Genes (13)

All genes assigned to this co-expression submodule.

Gene Type Publications

Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.

Gene Co-expression Network

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Low
High z