This 26-gene module includes PAK1, CNNM2, ARFGEF2, SCAI, and TRAK1, with enriched terms related to cytoskeleton organization, membrane trafficking, and protein transport. Knockdown of ARID1A, SMAD3, and MIXL1 activates this module. Knockdown of DR1, HES1, and SOX11 represses this module.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.