This 15-gene module includes BCL11A, RBPJ, AGO1, PDGFC, and WNK2, with enrichment in chromatin remodeling and transcriptional regulation processes. Knockdown of ARID1A, SMAD3, and MIXL1 activates this module. Knockdown of HES1 and SOX17 represses this module.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.