This module contains 19 genes including RUNX2, XIAP, MFSD8, FBH1, and ARHGEF18, with enrichment in bone morphogenesis, apoptotic processes, and cell differentiation. Knockdown of DNAJC19, ZC3H3, E2F6, and TCEB3 activates this module. Knockdown of TGIF1 and GATAD2A represses this module.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.