DE-1 ›

DE-1.24

Submodule 17 genes

Respiratory chain and oxidative phosphorylation

This 17-gene module includes PRMT1, PRDX2, ENO1, NDUFA13, and RBX1, with strong enrichment for respiratory chain complex, aerobic respiration, and oxidative phosphorylation processes. No transcription factor knockdown data are available for this module. No repressing transcription factors are identified.

Key terms: cellular respiration aerobic respiration oxidative phosphorylation energy derivation by oxidation of organic compounds Notable genes: PRMT1 PRDX2 ENO1 NDUFA13 RBX1 ATP5F1B CKB UBB

TF Regulatory Network

Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).

Evidence: Direction: Max binding-only shown:
Perturbation + Binding ↑ ↓
Perturbation only ↑ ↓
Binding only
TF Dir NES #gRNA padj Bind OR

Enriched Terms

GO terms and pathway annotations enriched in this gene set (g:Profiler).

Module Genes (17)

All genes assigned to this co-expression submodule.

Gene Type Publications

Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.

Gene Co-expression Network

| |
Low
High z
Huangfu Lab · Publications · Resources · Contact