DE-1

DE-1.18

Submodule 22 genes

mRNA processing and splicing regulation

This 22-gene module includes TFAM, KHDRBS1, DKC1, GNL3, and GGH, with enrichment in mRNA metabolic process, mRNA processing, and RNA splicing. Knockdown of SOX17 activates this module. No transcription factors repress this module based on the available data.


TF Regulatory Network

Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).

Evidence: Direction: Max binding-only shown:
Perturbation + Binding
Perturbation only
Binding only
TF Dir NES #gRNA padj Bind OR

Enriched Terms

GO terms and pathway annotations enriched in this gene set (g:Profiler).


Module Genes (22)

All genes assigned to this co-expression submodule.

Gene Type Publications

Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.

Gene Co-expression Network

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Low
High z