This module contains 25 genes including STUB1, RHOC, CD99, BCAP31, and CAPNS1, enriched for protein ubiquitination, endocytosis, and membrane trafficking functions. Knockdown of KLF6 activates this module. Knockdown of SOX4, SOX11, and LIN28A represses this module.
Direction indicates the effect of TF knockdown on this submodule (↑ = KD upregulates; ↓ = KD downregulates).
| TF | Dir | NES | #gRNA | padj | Bind | OR |
|---|
GO terms and pathway annotations enriched in this gene set (g:Profiler).
| Term | Source | p-value | Genes |
|---|
No significant enrichment terms.
All genes assigned to this co-expression submodule.
| Gene | Type | Publications |
|---|
Local co-expression graph for member genes built from Hotspot z-scores. Adjust the z-score threshold and repulsion sliders to explore the neighbourhood.